Zhang Rensheng V, Carr Brent R
Department of Anesthesiology, University of Florida College of Medicine, Gainesville, USA.
Department of Psychiatry, University of Florida College of Medicine, Gainesville, USA.
Cureus. 2024 Jul 29;16(7):e65654. doi: 10.7759/cureus.65654. eCollection 2024 Jul.
Anesthesia for electroconvulsive therapy (ECT) requires proper medications and airway management. Besides an induction agent such as methohexital, a neuromuscular blocker such as succinylcholine (SCh) is often given for muscle relaxation. To maintain the patient's oxygen saturation, mask ventilation is required due to this transient chemical paralysis even in the presence of adequate preoxygenation. A morbidly obese, middle-aged female experienced multiple life-threatening hypoxic episodes due to "bronchospasms" during prior ECT treatments. A drastic reduction in the SCh dose to about half of the original dose led to much smoother anesthesia courses with no more hypoxic episodes during subsequent ECT treatments. We believe that the lower dosing of SCh avoided a long period of chemical paralysis, which led to a quick return of spontaneous respiration, shortened the need for airway support, and therefore avoided hypoxic episodes in subsequent ECT treatments.
电休克治疗(ECT)的麻醉需要合适的药物和气道管理。除了像美索比妥这样的诱导剂外,通常还会给予琥珀酰胆碱(SCh)等神经肌肉阻滞剂以实现肌肉松弛。为维持患者的氧饱和度,即便进行了充分的预给氧,由于这种短暂的化学性麻痹仍需面罩通气。一名病态肥胖的中年女性在先前的ECT治疗期间因“支气管痉挛”经历了多次危及生命的缺氧发作。将SCh剂量大幅减少至原剂量的约一半,使得后续ECT治疗期间的麻醉过程更加平稳,不再出现缺氧发作。我们认为,较低剂量的SCh避免了长时间的化学性麻痹,从而使自主呼吸迅速恢复,缩短了气道支持的需求,进而避免了后续ECT治疗中的缺氧发作。