Zhang Xiang, Shi Weiwei, Wang Jun, Zhang Ruzhi
Department of Dermatology The Second Affiliated Hospital of Wannan Medical College Wuhu China.
Department of Dermatology Affiliated Hospital 2 of Nantong University Nantong China.
Clin Case Rep. 2024 Aug 27;12(9):e9369. doi: 10.1002/ccr3.9369. eCollection 2024 Sep.
This case illustrates the clinical heterogeneity of porokeratosis (PK), with a patient presenting with both disseminated superficial actinic PK-like facial lesions and PK of Mibelli-like lesions on the buttocks and lower limbs. Ultraviolet exposure, infection, and immunosuppression may contribute to the manifestation of multiple clinical forms in a single patient. Close monitoring for potential malignant transformation is essential, particularly in elderly patients with long disease duration and a history of oncological conditions.
该病例说明了汗孔角化症(PK)的临床异质性,一名患者面部出现播散性浅表光化性汗孔角化症样损害,臀部和下肢出现米贝利汗孔角化症样损害。紫外线暴露、感染和免疫抑制可能导致同一患者出现多种临床类型。密切监测潜在的恶性转化至关重要,尤其是对于病程长且有肿瘤病史的老年患者。