Waqar Muhammad Umer, Cohen Philip R, Fratila Simona
Dermatology, University of Oradea, Oradea, ROU.
Dermatology, University of California, Davis Medical Center, Sacramento, USA.
Cureus. 2022 Jul 16;14(7):e26923. doi: 10.7759/cureus.26923. eCollection 2022 Jul.
Porokeratosis describes a heterogenic group of keratinization disorders in which lesions are papules and plaques that demonstrate central atrophy surrounded by a hyperkeratotic margin. Clinical variants include not only porokeratosis of Mibelli, but also disseminated superficial, disseminated actinic superficial, linear, punctate, and palmaris et plantaris disseminata. Porokeratosis has a risk of malignant transformation. A woman with disseminated superficial actinic porokeratosis (DSAP) whose lesions presented as pruritic plaques and papules is described. The diagnosis was suspected clinically, supported by dermoscopy findings, and confirmed histologically. The condition-associated pruritus was managed symptomatically; her skin lesions will be monitored clinically. Clinical manifestations, dermatoscopic features, pathology findings, and treatment options for DSAP are summarized.
汗孔角化症描述了一组异质性的角化障碍,其皮损为丘疹和斑块,表现为中央萎缩并被角化过度的边缘所环绕。临床变型不仅包括米贝利汗孔角化症,还包括播散性浅表性、播散性光化性浅表性、线状、点状以及掌跖播散性汗孔角化症。汗孔角化症有恶变风险。本文描述了一名患有播散性光化性浅表性汗孔角化症(DSAP)的女性,其皮损表现为瘙痒性斑块和丘疹。临床怀疑诊断,皮肤镜检查结果支持该诊断,并经组织学确诊。对与该病相关的瘙痒进行了对症处理;对其皮肤损害将进行临床监测。总结了DSAP的临床表现、皮肤镜特征、病理表现及治疗选择。