Hu Liwei, Ye Xin, Zeng Xin, Duan Xiaohong, Xiu Qinghua, Ding Zhangfan, Liu Fan
State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases West China Hospital of Stomatology, Sichuan University.
West China School of Nursing, Sichuan University, Chengdu, China.
J Craniofac Surg. 2024 Aug 29;35(8):e730-3. doi: 10.1097/SCS.0000000000010499.
This study enrolled 60 patients aged 28 to 76 years who were oral malignancy undergoing radical surgery for more than 3 hours to assess the disinfection effect of povidone-iodine in oral and maxillofacial surgery which is a clean-contaminated wound. The authors collected and compared the sample from oral mucosa and counted the colony-forming units before disinfection, after disinfection for 10 minutes, 1, 2, 3, and 4 hours. The results showed that the oral bacterial colony-forming units significantly decreased after disinfecting with povidone-iodine and the effect existed for 2 hours and the colony-forming units of 3 hours after disinfection showed statistically significant increase. In oral and maxillofacial surgery, povidone-iodine can effectively disinfect the mouth and maintain a certain period of time. Therefore, to reduce the number of oral mucosa microorganisms, it is recommended to disinfect the oral cavity again after 3 hours.
本研究纳入了60例年龄在28至76岁之间、正在接受超过3小时根治性手术的口腔恶性肿瘤患者，以评估聚维酮碘在口腔颌面外科清洁-污染伤口中的消毒效果。作者收集并比较了口腔黏膜样本，并对消毒前、消毒10分钟后、1、2、3和4小时后的菌落形成单位进行计数。结果显示，用聚维酮碘消毒后口腔细菌菌落形成单位显著减少，且效果持续2小时，消毒3小时后的菌落形成单位有统计学意义的增加。在口腔颌面外科手术中，聚维酮碘可有效消毒口腔并维持一定时间。因此，为减少口腔黏膜微生物数量，建议在3小时后再次对口腔进行消毒。
