内镜反应可降低克罗恩病样储袋炎患者后续发生储袋炎的风险。
Endoscopic Response Reduces the Risk of Subsequent Pouchitis in Patients With Crohn's Disease-Like Pouch Inflammation.
作者信息
Kayal Maia, Posner Hannah, Jimenez Darwin, Huang Justin, Dubinsky Marla C, Colombel Jean Frederic
机构信息
Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York, USA .
出版信息
Am J Gastroenterol. 2025 Jan 1;120(1):251-253. doi: 10.14309/ajg.0000000000003055. Epub 2024 Aug 27.
INTRODUCTION
The aim of this study was to report the frequency and impact of endoscopic response and remission on the risk of subsequent pouchitis in patients with Crohn's disease-like pouch inflammation (CDLPI) on therapy.
METHODS
This was a single-center retrospective study of patients older than 18 years with CDLPI on therapy.
RESULTS
Among 110 included patients with CDLPI in clinical remission, endoscopic remission was not significantly associated with a reduced risk of subsequent pouchitis when compared with endoscopic response.
DISCUSSION
Endoscopic response, not remission, is sufficient to reduce the risk of subsequent pouchitis in patients with CDLPI.
引言
本研究的目的是报告内镜反应和缓解对接受治疗的克罗恩病样袋炎（CDLPI）患者后续发生袋炎风险的频率和影响。
方法
这是一项对18岁以上接受CDLPI治疗患者的单中心回顾性研究。
结果
在110例临床缓解的CDLPI患者中，与内镜反应相比，内镜缓解与后续袋炎风险降低无显著相关性。
讨论
内镜反应而非缓解足以降低CDLPI患者后续发生袋炎的风险。
Zotero 插件