Division of Gastrointestinal Surgery, Department of Surgery, University of South Florida Morsani College of Medicine, 5 Tampa General Circle, Tampa, FL, 33606, USA.
Hernia. 2024 Oct;28(5):1571-1576. doi: 10.1007/s10029-024-03136-3. Epub 2024 Aug 29.
Hiatal hernia recurrence rates vary widely. The true causes of recurrences are not fully understood but likely multifactorial. Surgical approaches and techniques have evolved over time to try and reduce recurrence rates after hiatal hernia repair. Our objective is to provide a current review on the physiology of hiatal hernias and the importance of a composite crural repair on hiatal hernia recurrence rates; more specifically, for this review, a composite repair is defined as a repair requiring more than primary closure of the crura.
A recent review of the literature was conducted to identify studies reporting on hiatal hernia pathophysiology, stress, and tension, as well as the role of composite repair.
There is a paucity of studies focusing on the pathophysiology of hiatal hernias and recurrence rates. Articles that report on the pathophysiology of the hiatus were found to have alterations of the extracellular matrix, collagen composition, changes in metalloproteinases (MMPs), and differences in genetic composition. The role of composite repair on reducing recurrence rates is not well studied.
Hiatal hernias remain a complex problem with no ideal surgical technique. It is likely that the pathophysiology of hiatal hernias is multifactorial, and more studies need to be done to better understand the potential underlying mechanisms for hiatal hernias so this may also further identify the ideal surgical repair.
食管裂孔疝的复发率差异很大。复发的真正原因尚未完全阐明,但可能是多因素的。随着时间的推移,外科手术方法和技术不断发展,试图降低食管裂孔疝修补术后的复发率。我们的目的是提供一篇关于食管裂孔疝生理学以及复合裂孔修补术对食管裂孔疝复发率的重要性的最新综述;更具体地说,对于本次综述,复合修补术定义为需要对裂孔进行不止一次的直接缝合的修补术。
最近对文献进行了回顾,以确定报告食管裂孔疝病理生理学、张力和压力以及复合修补术作用的研究。
目前关于食管裂孔疝病理生理学和复发率的研究较少。发现报告 hiatus 病理生理学的文章存在细胞外基质改变、胶原组成改变、金属蛋白酶 (MMP) 变化以及遗传组成差异。复合修补术降低复发率的作用尚未得到很好的研究。
食管裂孔疝仍然是一个复杂的问题,没有理想的手术技术。 hiatus 疝的病理生理学可能是多因素的,需要进行更多的研究来更好地理解 hiatus 疝的潜在机制,这也可能进一步确定理想的手术修复方法。