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心血管肿瘤学中的心血管成像。

Cardiovascular imaging in cardio-oncology.

机构信息

Kyoto College of Medical Science, Sonobe, Kyoto, Japan.

Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

出版信息

Jpn J Radiol. 2024 Dec;42(12):1372-1380. doi: 10.1007/s11604-024-01636-x. Epub 2024 Aug 29.

Abstract

Advances in cancer treatment have improved in patient survival rate. On the other hand, management of cardiovascular complications has been increasingly required in cancer patients. Thus, cardio-oncology has attracted the attention by both oncologists and cardiologists. Cardiovascular imaging has played a key role for non-invasive assessment of cardiovascular alterations complimentary to biomarkers and clinical assessment. Suitable imaging selection and interpretation may allow early diagnosis of cardiovascular injury with potential implications for therapeutic management and improved outcomes after cancer therapy. Echocardiography has been commonly used to evaluate cardiac dysfunction in cardio-oncology area. Cardiac CT is valuable for assessing structural abnormalities of the myocardium, coronary arteries, and aorta. Molecular imaging has an important role in the assessment of the pathophysiology and future treatment strategy of cardiovascular dysfunction. Cardiac MRI is valuable for characterization of myocardial tissue. PET and SPECT molecular imaging has potential roles for quantitative assessment of cardiovascular disorders. Particularly, FDG-PET is considered as an elegant approach for simultaneous assessment of tumor response to cancer therapy and early detection of possible cardiovascular involvement as well. This review describes the promising potential of these non-invasive cardiovascular imaging modalities in cardio-oncology.

摘要

癌症治疗的进展提高了患者的生存率。另一方面,癌症患者需要越来越多地管理心血管并发症。因此,肿瘤心脏病学引起了肿瘤学家和心脏病学家的关注。心血管成像在非侵入性评估心血管改变方面发挥了关键作用,补充了生物标志物和临床评估。合适的影像学选择和解释可以早期诊断心血管损伤,从而对治疗管理和癌症治疗后的预后改善产生潜在影响。超声心动图常用于评估肿瘤心脏病学领域的心脏功能障碍。心脏 CT 对评估心肌、冠状动脉和主动脉的结构异常很有价值。分子成像在评估心血管功能障碍的病理生理学和未来治疗策略方面具有重要作用。心脏 MRI 对心肌组织的特征具有重要价值。PET 和 SPECT 分子成像在定量评估心血管疾病方面具有潜在作用。特别是,FDG-PET 被认为是一种同时评估肿瘤对癌症治疗的反应和早期发现可能的心血管受累的优雅方法。本文综述了这些非侵入性心血管成像方式在肿瘤心脏病学中的应用前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b30/11588866/8207c1695b4d/11604_2024_1636_Fig1_HTML.jpg

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