Tamaki Nagara, Aikawa Tadao, Manabe Osamu
Kyoto University of Medical Science, Kyoto 622-0041, Japan.
Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.
Diagnostics (Basel). 2025 Feb 27;15(5):573. doi: 10.3390/diagnostics15050573.
Cardiovascular inflammation has recently emerged as a critical issue across various cardiovascular diseases. Various non-invasive imaging modalities are applied for assessing cardiovascular inflammation. Positron emission tomography (PET) using F-fluorodeoxyglucose (FDG) is a valuable non-invasive imaging tool for identifying active cardiovascular inflammation. It is utilized in evaluating conditions, such as cardiac sarcoidosis, endocarditis, vasculitis, and unstable atherosclerosis. Furthermore, management of cardiovascular complications after aggressive cancer therapy has increasingly been required in cancer patients. FDG PET is considered a suitable approach not only for the assessment of tumor responses to cancer therapy, but also for early and accurate detection of cardiovascular complications. This review highlights the clinical value of FDG PET under appropriate patient preparation. The future perspectives of new molecular imaging tools for assessing active cardiovascular inflammation have been described.
心血管炎症最近已成为各类心血管疾病中的一个关键问题。各种非侵入性成像方式被用于评估心血管炎症。使用氟脱氧葡萄糖（FDG）的正电子发射断层扫描（PET）是一种用于识别活跃心血管炎症的有价值的非侵入性成像工具。它被用于评估诸如心脏结节病、心内膜炎、血管炎和不稳定动脉粥样硬化等病症。此外，癌症患者对积极癌症治疗后心血管并发症的管理需求日益增加。FDG PET不仅被认为是评估肿瘤对癌症治疗反应的合适方法，也是早期准确检测心血管并发症的合适方法。本综述强调了在适当的患者准备下FDG PET的临床价值。还描述了用于评估活跃心血管炎症的新型分子成像工具的未来前景。
