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西部马脑炎:一例儿科病例报告。

Western equine encephalitis: a pediatric case report.

作者信息

González Pannia Paula, De Lillo Leonardo, Roldán Mónica, Miño Laura, Pruscino Florencia, Farias Eliana, Juárez Ximena

机构信息

Department of Medicine; Hospital General de Niños Pedro de Elizalde, City of Buenos Aires, Argentina.

Department of Epidemiology; Hospital General de Niños Pedro de Elizalde, City of Buenos Aires, Argentina.

出版信息

Arch Argent Pediatr. 2025 Feb 1;123(1):e202410392. doi: 10.5546/aap.2024-10392.eng. Epub 2024 Sep 5.

Abstract

Western equine encephalitis (WEE) is a zoonotic disease caused by an RNA virus of the genus Alphavirus, and humans are accidental hosts. Although most patients do not develop symptoms upon infection, children are at higher risk for neurological involvement. Here we describe the case of a previously healthy 13-year-old male patient who lived in an urban area in the province of Buenos Aires, Argentina, who was hospitalized and diagnosed with meningoencephalitis. Due to the torpid course of his condition and because none of the most frequent microorganisms were isolated, a test for IgG antibodies for WEE virus in blood and cerebrospinal fluid was requested; both samples were positive. WEE virus is often an underdiagnosed cause of encephalitis and should be taken into consideration in both rural and urban areas.

摘要

西部马脑炎(WEE)是一种由甲病毒属的RNA病毒引起的人畜共患病,人类是偶然宿主。虽然大多数患者感染后不会出现症状,但儿童发生神经系统受累的风险更高。在此,我们描述了一名先前健康的13岁男性患者的病例,该患者居住在阿根廷布宜诺斯艾利斯省的一个城市地区,因住院被诊断为脑膜脑炎。由于其病情进展缓慢,且未分离出任何最常见的微生物,因此要求对血液和脑脊液进行WEE病毒IgG抗体检测;两个样本均呈阳性。WEE病毒常常是脑炎的一个未被充分诊断的病因,在农村和城市地区均应予以考虑。

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