Department of Mathematics, University of Education, Lahore, Pakistan.
Mathematics Research Center, Near East University, Nicosia, North Cyprus, Turkey.
PLoS One. 2024 Aug 29;19(8):e0307732. doi: 10.1371/journal.pone.0307732. eCollection 2024.
In this research, we developed an epidemic model with a combination of Atangana-Baleanu Caputo derivative and classical operators for the hybrid operator's memory effects, allowing us to observe the dynamics and treatment effects at different time phases of syphilis infection caused by sex. The developed model properties, which take into account linear growth and Lipschitz requirements relating the rate of effects within its many sub-compartments according to the equilibrium points, include positivity, unique solution, exitance, and boundedness in the feasible domain. After conducting sensitivity analysis with various parameters influencing the model for the piecewise fractional operator, the reproductive number R0 for the biological viability of the model is determined. Generalized Ulam-Hyers stability results are employed to preserve global stability. The investigated model thus has a unique solution in the specified subinterval in light of the Banach conclusion, and contraction as a consequence holds for the Atangana-Baleanu Caputo derivative with classical operators. The piecewise model that has been suggested has a maximum of one solution. For numerical solutions, piecewise fractional hybrid operators at various fractional order values are solved using the Newton polynomial interpolation method. A comparison is also made between Caputo operator and the piecewise derivative proposed operator. This work improves our knowledge of the dynamics of syphilis and offers a solid framework for assessing the effectiveness of interventions for planning and making decisions to manage the illness.
在这项研究中,我们开发了一个结合了 Atangana-Baleanu Caputo 导数和经典算子的传染病模型,用于混合算子的记忆效应,使我们能够观察到性传播梅毒感染不同时间阶段的动态和治疗效果。所开发模型的特性考虑了线性增长和 Lipschitz 要求,根据平衡点,将许多子区域内的效应速率相关联,包括正定性、唯一解、存在性和可行域内的有界性。对分段分数算子影响模型的各种参数进行敏感性分析后,确定了模型的繁殖数 R0,以评估其生物学可行性。采用广义 Ulam-Hyers 稳定性结果来保持全局稳定性。根据 Banach 结论,在所指定的子区间内,所研究的模型具有唯一解,并且由于具有经典算子的 Atangana-Baleanu Caputo 导数,因此具有收缩性。所提出的分段模型最多只有一个解。对于数值解,使用牛顿多项式插值法求解不同分数阶值的分段分数混合算子。还比较了 Caputo 算子和所提出的分段导数算子。这项工作增进了我们对梅毒动力学的认识,并为评估干预措施的有效性提供了坚实的框架,以规划和做出决策来管理这种疾病。