Mor-Joseph S, Anteby S O, Granat M, Brzezinsky A, Evron S
Am J Obstet Gynecol. 1985 Apr 15;151(8):1085-6. doi: 10.1016/0002-9378(85)90389-8.
A 34-year-old patient, gravida 7, para 0, with three consecutive spontaneous abortions followed by four recurrent molar pregnancies is described. The patient conceived only with clomiphene citrate or human gonadotropin treatment. The occurrence of molar pregnancies succeeded spontaneous abortions with one remaining pregnancy progressing to gestational trophoblastic disease. The role of clomiphene citrate and human gonadotropins in the pathogenesis of this disease is discussed.
本文描述了一位34岁的患者，孕7产0，有三次连续自然流产，随后又有四次复发性葡萄胎妊娠。该患者仅通过枸橼酸氯米芬或人绒毛膜促性腺激素治疗受孕。葡萄胎妊娠发生在自然流产之后，其中一次妊娠进展为妊娠滋养细胞疾病。文中讨论了枸橼酸氯米芬和人绒毛膜促性腺激素在该疾病发病机制中的作用。
