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在没有留置导尿管的养老院居民中诊断可能的尿路感染:叙述性综述。

Diagnosing probable urinary tract infections in nursing home residents without indwelling catheters: a narrative review.

机构信息

Department of Public Health, Research Unit of General Practice, University of Southern Denmark, Odense, Denmark; Primary Care Research Institute Jordi Gol, Institut d'Investigació en Atenció Primària (IDIAP), Barcelona, Spain; CIBER Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain.

Primary Care Research Institute Jordi Gol, Institut d'Investigació en Atenció Primària (IDIAP), Barcelona, Spain; CIBER Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain; Department of General Pathology. University Rovira i Virgili, Tarragona, Spain.

出版信息

Clin Microbiol Infect. 2024 Dec;30(12):1523-1528. doi: 10.1016/j.cmi.2024.08.020. Epub 2024 Aug 30.

Abstract

BACKGROUND

Overdiagnosis of urinary tract infections (UTIs) is one of the most common reasons for the unnecessary use of antibiotics in nursing homes, increasing the risk of missing serious conditions. Various decision tools and algorithms aim to aid in UTI diagnosis and the initiation of antibiotic therapy for residents. However, due to the lack of a clear reference standard, these tools vary widely and can be complex, with some requiring urine testing. As part of the European-funded IMAGINE project, aimed at improving antibiotic use for UTIs in nursing home residents, we have reviewed the recommendations.

OBJECTIVES

This review provides a comprehensive summary of the more relevant tools and algorithms aimed at identifying true UTIs among residents living in nursing homes and discusses the challenges in using these algorithms based on updated research.

SOURCES

The discussion is based on a relevant medical literature search and synthesis of the findings and published tools to provide an overview of the current state of improving the diagnosis of UTIs in nursing homes.

CONTENT

The following topics are covered: prevalence of asymptomatic bacteriuria, diagnostic challenges, clinical criteria, urinary testing, and algorithms to be implemented in nursing home facilities.

IMPLICATIONS

Diagnosing UTIs in residents is challenging due to the high prevalence of asymptomatic bacteriuria and nonspecific urinary tract signs and symptoms among those with suspected UTIs. The fear of missing a UTI and the perceived antibiotic demands from residents and relatives might lead to overdiagnosis of this common condition. Despite their widespread use, urine dipsticks should not be recommended for geriatric patients. Patients who do not meet the minimum diagnostic criteria for UTIs should be evaluated for alternative conditions. Adherence to a simple algorithm can prevent unnecessary antibiotic courses without compromising resident safety.

摘要

背景

在养老院中,过度诊断尿路感染(UTI)是不必要使用抗生素的最常见原因之一,这增加了漏诊严重疾病的风险。各种决策工具和算法旨在帮助诊断 UTI 并为居民开始抗生素治疗。然而,由于缺乏明确的参考标准,这些工具差异很大,并且可能很复杂,其中一些需要进行尿液检测。作为旨在改善养老院居民 UTI 抗生素使用的欧洲资助项目 IMAGINE 的一部分,我们对建议进行了审查。

目的

本综述全面总结了更相关的工具和算法,旨在识别居住在养老院中的居民中真正的 UTI,并根据最新研究讨论使用这些算法的挑战。

来源

讨论基于相关医学文献检索和研究结果的综合,以及已发表的工具,以提供改善养老院 UTI 诊断现状的概述。

内容

涵盖以下主题:无症状菌尿的患病率、诊断挑战、临床标准、尿液检测以及要在养老院设施中实施的算法。

意义

由于无症状菌尿和疑似 UTI 患者的尿路非特异性体征和症状的高患病率,诊断居民的 UTI 具有挑战性。担心漏诊 UTI 以及居民和亲属对使用抗生素的期望可能导致这种常见疾病的过度诊断。尽管它们被广泛使用,但不建议将尿液试纸用于老年患者。不符合 UTI 最低诊断标准的患者应评估替代疾病。遵循简单的算法可以在不影响居民安全的情况下预防不必要的抗生素疗程。

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