评估低危宫颈癌的微创单纯子宫切除术：LASH 试验的设定。
Assessing minimally invasive simple hysterectomy in low risk cervical cancer: set up for the LASH trial.
机构信息
UOC Ginecologia Oncologica, Dipartimento di Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
出版信息
Int J Gynecol Cancer. 2024 Nov 4;34(11):1805-1808. doi: 10.1136/ijgc-2024-005941.
After the publication of the Laparoscopic Approach to Cervical Cancer (LACC) trial, open surgery has become the standard approach for radical hysterectomy in early stage cervical cancer. Recent studies assessed the role of a non-radical approach in low risk cervical cancer and showed no survival difference compared with radical hysterectomy. However, there is a gap in knowledge regarding the oncologic outcomes of minimally invasive simple hysterectomy in low risk cervical cancer. This review offers an overview of the current evidence on the role of the minimally invasive approach in low risk cervical cancer and raises the need for a new clinical trial in this setting.
LACC 试验发表后，开放式手术已成为早期宫颈癌根治性子宫切除术的标准方法。最近的研究评估了非根治性方法在低危宫颈癌中的作用，与根治性子宫切除术相比，没有生存差异。然而，对于微创单纯子宫切除术在低危宫颈癌中的肿瘤学结果，知识上仍存在差距。本综述概述了微创方法在低危宫颈癌中的作用的现有证据，并提出了在这一背景下开展新临床试验的必要性。
Zotero 插件