Royal North Shore Hospital, St Leonards, New South Wales, Australia
Royal North Shore Hospital, St Leonards, New South Wales, Australia.
BMJ Case Rep. 2024 Aug 29;17(8):e260317. doi: 10.1136/bcr-2024-260317.
Acinar cystic transformation (ACT) of the pancreas is a rare non-neoplastic cystic lesion. It is difficult to distinguish from more concerning pathology, particularly a side-branch duct intraductal papillary mucinous neoplasm (IPMN). All reported cases of ACT have been clinically benign with no evidence of recurrence or malignant transformation. The Fukuoka guidelines is a classification system designed to help guide the management of IPMNs and mucinous cystic neoplasms. We report a case of ACT that was preoperatively diagnosed as a suspected side-branch IPMN. Through the application of current guidelines, the patient underwent a Whipple's procedure. We highlight the difficulties in obtaining an accurate preoperative diagnosis in cases of ACT and the current radiological and cytological methods available to clinicians.
胰腺腺泡囊性转化（ACT）是一种罕见的非肿瘤性囊性病变。它很难与更令人担忧的病变区分开来，特别是分支胰管内乳头状黏液性肿瘤（IPMN）。所有报道的 ACT 病例均为临床良性，无复发或恶性转化的证据。福冈指南是一个旨在帮助指导 IPMN 和黏液性囊性肿瘤管理的分类系统。我们报告了一例术前诊断为可疑分支 IPMN 的 ACT 病例。通过应用当前的指南，患者接受了胰十二指肠切除术。我们强调了在 ACT 病例中获得准确术前诊断的困难，以及目前临床医生可用的放射学和细胞学方法。
