Mental Health and Specialist Services, Gold Coast Health, Southport, QLD, Australia.
Mental Health and Specialist Services, Gold Coast Health, Southport, QLD, Australia; School of Medicine, Bond University, Robina, QLD, Australia; and Catherine's House for Mothers, Babies and Families, Mater Research Institute, The University of Queensland, South Brisbane, QLD, Australia.
Australas Psychiatry. 2024 Dec;32(6):573-581. doi: 10.1177/10398562241278856. Epub 2024 Aug 29.
The purpose of this study was to understand the pharmacotherapy and electroconvulsive therapy (ECT) prescription of women with depression and anxiety admitted to an Australian inpatient psychiatric mother-baby unit (MBU) and compare prescription to national clinical practice guidelines.
A retrospective audit was conducted on women diagnosed with depression or anxiety admitted to a public psychiatric inpatient MBU from March 2017 to July 2019. Data was captured at three time points to assess demographic, clinical and pharmacotherapy treatment characteristics. Descriptive statistics were completed.
Of the 74 women, 57 women had depression, with 73% prescribed Selective Serotonin Reuptake Inhibitors (SSRIs) and 14% provided ECT during admission. For women with anxiety ( = 17), 23% were prescribed a benzodiazepine with concurrent antidepressant prescription. SSRI prescription increased, with other antidepressant prescription up trending through admission. Atypical antipsychotic prescription was increased initially and trended downwards at discharge.
This study explored the therapeutic armamentarium employed for the treatment of mothers admitted to an inpatient psychiatric MBU with depression and anxiety. The results point to the intricate prescribing practices in a naturalistic setting and highlight that prescribing practices were in line with national guidelines.
本研究旨在了解澳大利亚住院精神病母婴单位(MBU)中抑郁和焦虑女性的药物治疗和电惊厥治疗(ECT)处方情况,并将其与国家临床实践指南进行比较。
对 2017 年 3 月至 2019 年 7 月期间在一家公立精神病住院 MBU 就诊的被诊断为抑郁或焦虑的女性进行了回顾性审核。数据在三个时间点采集,以评估人口统计学、临床和药物治疗特征。完成了描述性统计。
在 74 名女性中,57 名女性患有抑郁症,其中 73%的患者被开具选择性 5-羟色胺再摄取抑制剂(SSRIs),14%的患者在住院期间接受 ECT。对于患有焦虑症的女性(n=17),23%的患者同时开具了苯二氮䓬类药物和抗抑郁药。SSRIs 的处方增加,而其他抗抑郁药的处方在住院期间呈上升趋势。非典型抗精神病药的处方最初增加,在出院时呈下降趋势。
本研究探讨了用于治疗住院精神病母婴单位中抑郁和焦虑母亲的治疗手段。结果指出了在自然环境中复杂的处方实践,并强调了处方实践符合国家指南。