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[严重肾功能不全及透析患者的心脏直视手术]

[Open heart cardiac surgery in severe renal insufficiency and dialysis patients].

作者信息

Pavie A, Mussat T, Valle D, Rottembourg J, Barthélémy A, Gandjbakhch I, Legrain M, Cabrol C

出版信息

Arch Mal Coeur Vaiss. 1985 Feb;78(2):242-7.

PMID:3920994
Abstract

Surgically remediable cardiovascular complications are common in patients with renal failure treated by dialysis. 20 such patients were operated in our department (16 men and 4 women), aged 27 to 61 years (mean 44.5 years). 12 patients had undergone haemodialysis for 1 to 84 months; 4 patients were treated by peritoneal dialysis; the remaining four patients all had severe renal failure with creatinine clearances of less than 10 ml per minute. All patients were operated immediately after a session of dialysis. Particular attention was paid to preserving the peripheral arterial and venous vessels during anaesthesia and cardiopulmonary bypass. The jugular veins were used whenever possible to spare the upper limb veins and the dorsalis pedis arteries were used for the monitoring of systemic blood pressure to spare the radial arteries for eventual arteriovenous fistulae. Weight gain during the operation was limited by cardiopulmonary bypass techniques. The circuit was filled with 200 cc of B 21, 500 cc of isotonic bicarbonate solution and 800 cc of frozen plasma with potassium supplements. Mean weight gain was moderate (1.1 +/- 0.4 kg). 12 patients underwent valve replacement. The surgical indication was acute endocarditis in 6 cases. The aortic valve was replaced in 10 cases and the mitral valve in 2 cases by mechanical valve prostheses because of the high risk of calcification of bioprostheses in severe renal failure. 8 patients underwent coronary bypass graft surgery. Arterial blood pressure was maintained at over 60 mmHg and large doses of heparin were used to protect the arteriovenous shunts.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在接受透析治疗的肾衰竭患者中,可通过手术治疗的心血管并发症很常见。我科对20例此类患者进行了手术(16例男性,4例女性),年龄在27至61岁之间(平均44.5岁)。12例患者接受血液透析1至84个月;4例患者接受腹膜透析治疗;其余4例患者均患有严重肾衰竭,肌酐清除率低于每分钟10毫升。所有患者在一次透析后立即进行手术。在麻醉和体外循环期间,特别注意保护外周动脉和静脉血管。尽可能使用颈静脉以保留上肢静脉,使用足背动脉监测全身血压以保留桡动脉用于最终的动静脉内瘘。手术期间的体重增加通过体外循环技术加以限制。体外循环回路中填充200毫升B 21、500毫升等渗碳酸氢盐溶液和800毫升补充钾的冷冻血浆。平均体重增加适中(1.1±0.4千克)。12例患者接受了瓣膜置换术。手术指征为6例急性心内膜炎。由于严重肾衰竭患者生物假体钙化风险高,10例患者置换主动脉瓣,2例患者置换二尖瓣,均使用机械瓣膜假体。8例患者接受了冠状动脉搭桥手术。动脉血压维持在60毫米汞柱以上,并使用大剂量肝素保护动静脉分流。(摘要截短至250字)

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