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[慢性血液透析患者的心脏手术:近期和长期结果]

[Cardiac surgery in chronic hemodialysed patients: immediate and long-term results].

作者信息

Deleuze P H, Mazzucotelli J P, Maillet J M, Le Besnerais P, Mourtada A, Hillion M L, Loisance D Y, Cachera J P

机构信息

Service de chirurgie thoracique et cardiovasculaire, hôpital Henri-Mondor, Créteil.

出版信息

Arch Mal Coeur Vaiss. 1995 Jan;88(1):43-8.

PMID:7646248
Abstract

Between 1979 and 1993, 50 patients (33 men and 17 women) receiving chronic haemodialysis, underwent 53 cardiac surgical procedures in the department. The mean age was 56 +/- 13 years. The average duration of preoperative dialysis was 82 +/- 63 months. The average duration of cardiac symptoms before surgery was 35 +/- 52 months. Twenty-seven patients (54%) were in NYHA functional classes III or IV before surgery. Sixteen patients (32%) had preoperative left ventricular ejection fractions of less than 0.40. Twelve patients (24%) were emergency referrals. Twenty-nine patients underwent isolated coronary bypass surgery, 13 patients underwent isolated aortic valvular replacement which had to be repeated in one case, 3 patients underwent mitral valve replacement, which had to be repeated in 2 cases, and 5 patients underwent combined surgery. The average aortic clamping time was 75 +/- 32 minutes, the average cardio-pulmonary bypass time was 125 +/- 50 minutes. The surgical revascularisation of the coronary patients was incomplete in 37% of cases because of the severity of the underlying coronary artery disease. The average postoperative bleeding was 800 +/- 650 ml; 29 patients (58%) were transfused with an average of 4.3 +/- 3 units of blood. The global early mortality was 9 patients (18%); 10% in coronary bypass, 7% in aortic valve replacement and 50% in patients with more complex procedures. The causes of death were cardiac (n = 4), sepsis (n = 2) and multiple organ failure (n = 3). The morbidity was 39%, mainly due to low cardiac output.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1979年至1993年间,该科室对50例接受慢性血液透析的患者(33例男性和17例女性)进行了53例心脏外科手术。平均年龄为56±13岁。术前透析的平均时长为82±63个月。术前心脏症状的平均持续时间为35±52个月。27例患者(54%)术前处于纽约心脏协会(NYHA)心功能Ⅲ级或Ⅳ级。16例患者(32%)术前左心室射血分数低于0.40。12例患者(24%)为急诊转诊。29例患者接受了单纯冠状动脉搭桥手术,13例患者接受了单纯主动脉瓣置换手术,其中1例需再次手术,3例患者接受了二尖瓣置换手术,其中2例需再次手术,5例患者接受了联合手术。平均主动脉阻断时间为75±32分钟,平均体外循环时间为125±50分钟。由于潜在冠状动脉疾病的严重程度,37%的冠状动脉患者手术血运重建不完全。术后平均失血量为800±650毫升;29例患者(58%)接受了输血,平均输血量为4.3±3单位。总体早期死亡率为9例患者(18%);冠状动脉搭桥手术患者中为10%,主动脉瓣置换手术患者中为7%,更复杂手术患者中为50%。死亡原因包括心脏原因(n = 4)、败血症(n = 2)和多器官功能衰竭(n = 3)。发病率为39%,主要原因是心输出量低。(摘要截断于250字)

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