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开窗髓核切除术与 iLESSYS-Delta 经皮椎间孔内镜系统治疗腰椎间盘突出症的临床疗效:单中心回顾性队列研究。

Clinical outcomes of fenestration discectomy and iLESSYS-Delta interlaminar endoscopic system for treatment of LDH: a single-center retrospective cohort study.

机构信息

Department of Orthopedics, Qilu Hospital of Shandong University, Jinan, 250012, People's Republic of China.

Yantaishan Hospital, Yantai, 264003, Shandong, People's Republic of China.

出版信息

Sci Rep. 2024 Aug 29;14(1):20087. doi: 10.1038/s41598-024-70973-8.

Abstract

To compare the clinical efficacy of interlaminar endoscopic surgical system delta (iLESSYS-Delta) discectomy with that of classical fenestration discectomy for treating lumbar disc herniation. Patients who underwent iLESSYS-Delta or fenestration discectomy were enrolled in this study. Baseline information and clinical indicators were collected. The baseline data were matched using propensity score matching. Fifty-two patients were in each group. In the iLESSYS-Delta cohort, the volume of intraoperative bleeding was 18.17 ± 4.20 ml, the length of postoperative hospital stay was 4.16 ± 2.29 days, and the length of postoperative off-bed activity was 1.58 ± 0.88 days. In contrast, in the fenestration group, the volume of intraoperative bleeding was 32.50 ± 17.13 ml, the length of postoperative hospital stay was 6.66 ± 2.44 days, and the length of postoperative off-bed activity was 3.18 ± 1.28 days. The difference between the two groups was statistically significant (P < 0.05). The operation time was 88.90 ± 19.14 min in the iLESSYS-Delta group and 67.63 ± 19.32 min in the fenestration group, and the difference between the two groups was statistically significant (P < 0.05). Regarding the pain visual analogue scale scores at 24, 48, and 72 h after surgery, patients in the iLESSYS-Delta group had less pain than did those in the fenestration group (P < 0.05). The Oswestry disability indices of postoperative patients in both groups significantly improved at 3 months after surgery and at the last follow-up (P < 0.05); however, there was no statistically significant difference in the postoperative ODI scores between the two surgery groups (P > 0.05). The two groups showed no significant differences in clinical effects, postoperative recurrence rates, or perioperative complications. iLESSYS-Delta can cause less intraoperative bleeding and faster recovery than fenestration discectomy.

摘要

为了比较经皮内窥镜下腰椎间融合术 delta(iLESSYS-Delta)椎间盘切除术与经典开窗椎间盘切除术治疗腰椎间盘突出症的临床疗效,本研究纳入了接受 iLESSYS-Delta 或开窗椎间盘切除术的患者。收集基线信息和临床指标。使用倾向评分匹配对基线数据进行匹配。每组 52 例。在 iLESSYS-Delta 组中,术中出血量为 18.17±4.20ml,术后住院时间为 4.16±2.29 天,术后离床活动时间为 1.58±0.88 天。相比之下,在开窗组中,术中出血量为 32.50±17.13ml,术后住院时间为 6.66±2.44 天,术后离床活动时间为 3.18±1.28 天。两组间差异具有统计学意义(P<0.05)。iLESSYS-Delta 组的手术时间为 88.90±19.14min,开窗组为 67.63±19.32min,两组间差异具有统计学意义(P<0.05)。术后 24、48、72h 时,iLESSYS-Delta 组患者疼痛视觉模拟评分均低于开窗组(P<0.05)。两组患者术后 Oswestry 功能障碍指数均于术后 3 个月及末次随访时显著改善(P<0.05);但两组术后 ODI 评分比较差异无统计学意义(P>0.05)。两组临床效果、术后复发率及围手术期并发症比较差异均无统计学意义(P>0.05)。iLESSYS-Delta 可引起比开窗椎间盘切除术更少的术中出血和更快的恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/370a/11362142/3c5a3091fb8f/41598_2024_70973_Fig1_HTML.jpg

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