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一种用于治疗膀胱膨出的自然组织修复的新型缝合技术。

A novel suturing technique for natural tissue repair in cystocele treatment.

机构信息

Department of Obstetrics and Gynecology, Ankara City Hospital (MH5), , Bilkent/Ankara, Turkey.

Department of Biostatistics, Hacettepe University, Ankara, Turkey.

出版信息

BMC Womens Health. 2024 Aug 29;24(1):474. doi: 10.1186/s12905-024-03317-3.

DOI:10.1186/s12905-024-03317-3
PMID:39210362
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11360469/
Abstract

BACKGROUND

Recently, natural tissue repair has become popular in the treatment of pelvic organ prolapsed. In this study, we compared patients who underwent cystocele repair with the rug-weaving plication technique, a natural tissue repair method implemented since 2022 for anterior prolapse, with those treated using conventional colporrhaphy.

METHODS

We retrospectively reviewed the data of 65 patients who underwent anterior vaginal wall repair with the rug-weaving plication technique (n = 33, Group 1) or conventional colporrhaphy (n = 32, Group 2). We recorded the patients' clinicodemographic and surgical data. At the 6-month postoperative follow-up, we assessed patients' complaints, degree of prolapse (using the simplified Pelvic Organ Prolapse Quantification system), and pelvic floor muscle strength (using the Modified Oxford Score). Anterior vaginal wall thickness was measured using transvaginal ultrasonography. We compared clinicodemographic and surgical data and postoperative outcomes between the two groups.

RESULTS

The two groups were comparable in terms of age (p = 0.326), number of pregnancies (p = 0.307), number of parities (p = 0.555), preoperative anterior wall simplified Pelvic Organ Prolapse Quantification grade (p = 0.380), preoperative apical prolapse simplified Pelvic Organ Prolapse Quantification grade (p = 0.518), postoperative Modified Oxford Score (p = 0.857), operation time (p = 0.809), postoperative haemoglobin (p = 0.674), and amount of bleeding (p = 0.951). Compared with Group 2, Group 1 had significantly higher postoperative anterior vaginal wall thickness (p < 0.001) and significantly lower postoperative anterior wall simplified Pelvic Organ Prolapse Quantification grade (p < 0.001).

CONCLUSIONS

The rug-weaving plication technique may offer a viable alternative for cystocele repair without mesh, using natural tissue and potentially reducing mesh-related complications and recurrence rates.

CLINICAL TRIAL NUMBER

NCT06410469 (03/05/2024).

摘要

背景

最近,自然组织修复在治疗盆腔器官脱垂方面变得流行。在这项研究中,我们比较了 2022 年以来采用 rug-weaving 折叠技术(一种用于前位脱垂的自然组织修复方法)治疗的膀胱膨出患者与采用传统阴道前壁修补术治疗的患者。

方法

我们回顾性分析了 65 例采用 rug-weaving 折叠技术(n=33,第 1 组)或传统阴道前壁修补术(n=32,第 2 组)治疗的前阴道壁修复患者的数据。记录患者的临床和手术数据。在术后 6 个月的随访中,评估患者的症状、脱垂程度(简化盆腔器官脱垂量化系统)和盆底肌肉力量(改良牛津评分)。使用经阴道超声测量前阴道壁厚度。比较两组的临床和手术数据及术后结果。

结果

两组在年龄(p=0.326)、妊娠次数(p=0.307)、产次(p=0.555)、术前前壁简化盆腔器官脱垂量化分级(p=0.380)、术前顶脱垂简化盆腔器官脱垂量化分级(p=0.518)、术后改良牛津评分(p=0.857)、手术时间(p=0.809)、术后血红蛋白(p=0.674)和出血量(p=0.951)方面无统计学差异。与第 2 组相比,第 1 组术后前阴道壁厚度明显增加(p<0.001),术后前壁简化盆腔器官脱垂量化分级明显降低(p<0.001)。

结论

与使用网片的传统阴道前壁修补术相比,rug-weaving 折叠技术可能是一种可行的无网片膀胱膨出修复方法,使用天然组织,可能降低网片相关并发症和复发率。

临床试验编号

NCT06410469(2024 年 03 月 05 日)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93dd/11360469/a6c03a6e2859/12905_2024_3317_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93dd/11360469/821a1524afe0/12905_2024_3317_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93dd/11360469/a6c03a6e2859/12905_2024_3317_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93dd/11360469/821a1524afe0/12905_2024_3317_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93dd/11360469/a6c03a6e2859/12905_2024_3317_Fig2_HTML.jpg

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本文引用的文献

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BMC Surg. 2024 Apr 13;24(1):106. doi: 10.1186/s12893-024-02368-5.
2
Does variation of surgical technique affect native tissue anterior pelvic organ prolapse repair outcomes?手术技术的变化是否会影响原发性组织前盆腔器官脱垂修复的结果?
Int Urogynecol J. 2024 Jan;35(1):51-58. doi: 10.1007/s00192-023-05584-4. Epub 2023 Jul 21.
3
Risk factors for postoperative pain after cystocele repair with mesh.使用网片进行膀胱膨出修补术后疼痛的危险因素。
Int Urogynecol J. 2023 Mar;34(3):771-775. doi: 10.1007/s00192-022-05285-4. Epub 2022 Sep 5.
4
Native tissue repair (NTR) versus transvaginal mesh interventions for the treatment of anterior vaginal prolapse: Systematic review and meta-analysis.经阴道自然组织修复术与经阴道网片修补术治疗阴道前壁膨出的比较:系统评价和荟萃分析。
Maturitas. 2022 Nov;165:104-112. doi: 10.1016/j.maturitas.2022.07.013. Epub 2022 Aug 3.
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A pilot study to evaluate changes in pelvic floor muscle tone following pelvic organ prolapse surgery using a novel intra-vaginal pressure sensor device.一项使用新型阴道内压力传感器设备评估盆腔器官脱垂手术后盆底肌张力变化的初步研究。
Int Urogynecol J. 2023 May;34(5):1043-1047. doi: 10.1007/s00192-022-05312-4. Epub 2022 Aug 8.
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Int J Surg Case Rep. 2022 Jun;95:107198. doi: 10.1016/j.ijscr.2022.107198. Epub 2022 May 16.
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