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病例报告：急性心肌梗死登记处C反应蛋白血液滤过治疗非ST段抬高型急性冠状动脉综合征病例系列

Case Report: C-reactive protein apheresis in non-ST-elevation ACS-case series from the C-reactive protein apheresis in Acute Myocardial Infarction Registry.

作者信息

Torzewski J, Mattecka S, Esposito F, Heigl F, Fiedler J, Sheriff A

机构信息

Cardiovascular Center Oberallgaeu-Kempten, Clinic Association Allgaeu, Kempten, Germany.

Pentracor GmbH, Hennigsdorf, Germany.

出版信息

Front Cardiovasc Med. 2024 Aug 15;11:1401566. doi: 10.3389/fcvm.2024.1401566. eCollection 2024.

DOI:10.3389/fcvm.2024.1401566
PMID:39211771
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11357922/
Abstract

C-reactive protein (CRP) apheresis has been introduced in ST-elevation myocardial infarction and cardiogenic shock. Here, we describe a first-in-man application in non-ST-elevation acute coronary syndrome (NSTE-ACS). Seven NSTE-ACS patients with high CRP levels (range 14.2-154 mg/L) were treated with CRP apheresis. Treatment was well-tolerated. Patients were discharged in good clinical condition.

摘要

C反应蛋白（CRP）吸附疗法已应用于ST段抬高型心肌梗死和心源性休克。在此，我们描述其在非ST段抬高型急性冠状动脉综合征（NSTE-ACS）中的首例人体应用。7例CRP水平较高（范围为14.2 - 154mg/L）的NSTE-ACS患者接受了CRP吸附治疗。治疗耐受性良好。患者出院时临床状况良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e73/11357922/e8e1ce657f8d/fcvm-11-1401566-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e73/11357922/e8e1ce657f8d/fcvm-11-1401566-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e73/11357922/e8e1ce657f8d/fcvm-11-1401566-g001.jpg

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2023 ESC Guidelines for the management of acute coronary syndromes.2023年欧洲心脏病学会急性冠状动脉综合征管理指南。
Eur Heart J. 2023 Oct 12;44(38):3720-3826. doi: 10.1093/eurheartj/ehad191.
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Seven COVID-19 Patients Treated with C-Reactive Protein (CRP) Apheresis.7例接受C反应蛋白（CRP）血液成分单采治疗的新冠肺炎患者。
J Clin Med. 2022 Apr 1;11(7):1956. doi: 10.3390/jcm11071956.
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Targeting C-Reactive Protein by Selective Apheresis in Humans: Pros and Cons.人类中通过选择性血液成分分离术靶向C反应蛋白：利弊
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