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利多卡因与硫酸镁在伴有症状性不可逆性牙髓炎的患者下颌神经阻滞麻醉中的效果比较:一项随机、双盲临床试验。

Effectiveness of Lidocaine versus Lidocaine with Magnesium Sulphate During Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Randomised Double-Blinded Clinical Trial.

机构信息

Department of Conservative Dentistry and Endodontics, Indira Gandhi Institute of Dental Sciences, Sri Balaji Vidyapeeth, Pondicherry, India.

Department of Conservative Dentistry and Endodontics, Rajas Dental College and Hospital, Tamil Nadu, India.

出版信息

Eur Endod J. 2024 Aug;9(3):198-202. doi: 10.14744/eej.2024.58569.

DOI:10.14744/eej.2024.58569
PMID:39213456
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11413603/
Abstract

OBJECTIVE

This study aimed to compare the effectiveness of lidocaine with magnesium sulphate in patients undergoing root canal treatment following irreversible pulpitis.

METHODS

A total of 86 patients were randomised to receive 1.8 ml of 2% lidocaine replaced with 0.2 ml of 10% magnesium sulphate with 1: 80,000 epinephrine (n=43) as MGS group and 1.8 ml of 2% lidocaine with 1: 80,000 epinephrine (n=43) as LDC group. Preoperative visual analogue scale (VAS) pain scores were record-ed. Patients were instructed to report any perioperative pain felt during the access cavity preparation and when introducing the first patency file (#10 k) in the root canal and perioperative VAS recorded.

RESULTS

The success rate of the inferior alveolar nerve block (IANB) was higher in the MSG group. The mean+-SD of perioperative pain was 0.16+-0.37 in the MSG group and 3.13+-0.77 in the LDC group. The MGS group produced better anaesthetic efficacy with a p-value of 0.01.

CONCLUSION

Based on the results, adding 10% magnesium sulphate to 2% lidocaine increased the effective-ness of IANB in patients with symptomatic irreversible pulpitis of mandibular molar teeth.

摘要

目的

本研究旨在比较利多卡因与硫酸镁在患有不可复性牙髓炎行根管治疗患者中的疗效。

方法

86 例患者随机分为两组,每组 43 例。观察组接受 1.8 ml 2%利多卡因加 0.2 ml 10%硫酸镁(内含 1:80000 肾上腺素),对照组接受 1.8 ml 2%利多卡因加 1:80000 肾上腺素。记录术前视觉模拟评分(VAS)疼痛评分。嘱患者记录在开髓和引入根管首支锉(#10 k)时感觉到的任何围手术期疼痛,并记录围手术期 VAS。

结果

MSG 组下牙槽神经阻滞(IANB)成功率较高。MSG 组围手术期疼痛的均值+-标准差为 0.16+-0.37,LDC 组为 3.13+-0.77。MSG 组的麻醉效果优于 LDC 组,p 值为 0.01。

结论

根据结果,在 2%利多卡因中加入 10%硫酸镁可提高有症状的下颌磨牙不可复性牙髓炎患者 IANB 的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ac/11413603/aa92087f9c7c/EEJ-9-198-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ac/11413603/74a226667c15/EEJ-9-198-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ac/11413603/aa92087f9c7c/EEJ-9-198-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ac/11413603/74a226667c15/EEJ-9-198-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ac/11413603/aa92087f9c7c/EEJ-9-198-g002.jpg

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