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额部纤维性脱发的毛囊外皮肤表现。

Extra-follicular cutaneous manifestations of frontal fibrosing alopecia.

机构信息

Trichology Outpatient Clinic, Hospital do Servidor Público Municipal de São Paulo, São Paulo, SP, Brazil.

Trichology Outpatient Clinic, Hospital do Servidor Público Municipal de São Paulo, São Paulo, SP, Brazil; Laser Outpatient Clinic, Hospital das Clínicas, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil.

出版信息

An Bras Dermatol. 2024 Nov-Dec;99(6):875-886. doi: 10.1016/j.abd.2024.01.003. Epub 2024 Aug 30.

DOI:10.1016/j.abd.2024.01.003
PMID:39214818
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11551274/
Abstract

Frontal fibrosing alopecia (FFA) is an inflammatory cicatricial alopecia, which is considered to be a variant of lichen planopilaris. In addition to follicular changes, FFA often presents with associated cutaneous manifestations in most patients, including lichen planus pigmentosus, implantation line hypochromia and facial papules. The objective of the present article is to provide a detailed overview of the non-follicular cutaneous clinical manifestations of FFA and discuss their impact on the diagnosis and treatment of patients with this condition.

摘要

额部纤维性瘢痕性脱发（FFA）是一种炎症性瘢痕性脱发，被认为是扁平苔藓样瘢痕性脱发的一种变异型。除了毛囊变化外，FFA 通常在大多数患者中还伴有相关的皮肤表现，包括色素性扁平苔藓、植入线色素减退和面部丘疹。本文的目的是详细概述 FFA 的非毛囊性皮肤临床表现，并讨论其对该疾病患者的诊断和治疗的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/2389aedec7aa/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/6b2cb8df3d28/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/0fc0dcdf6a1d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/ba54d3a591e2/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/9b68f1a16aca/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/c379e3007f95/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/490dd1524acd/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/b998cad69031/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/74f72341cc2b/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/2389aedec7aa/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/6b2cb8df3d28/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/0fc0dcdf6a1d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/ba54d3a591e2/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/9b68f1a16aca/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/c379e3007f95/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/490dd1524acd/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/b998cad69031/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/74f72341cc2b/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e75b/11551274/2389aedec7aa/gr9.jpg

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本文引用的文献

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Coexistence of vitiligo and frontal fibrosing alopecia: A case report and analysis of its physiopathology.白癜风与额部纤维性秃发并存：一例报告及其病理生理学分析
Actas Dermosifiliogr. 2022 Nov-Dec;113(10):991-994. doi: 10.1016/j.ad.2021.01.015. Epub 2021 Sep 16.
2
Frontiers in Lichen Planopilaris and Frontal Fibrosing Alopecia Research: Pathobiology Progress and Translational Horizons.扁平苔藓性毛发脱失和额部纤维性秃发研究前沿：病理生物学进展与转化前景
JID Innov. 2022 Mar 1;2(3):100113. doi: 10.1016/j.xjidi.2022.100113. eCollection 2022 May.
3
Follicular Melanocytes in Frontal Fibrosing Alopecia: An Immunohistochemical Study With Trichoscopic Correlation.
额部纤维性脱发中的毛囊黑素细胞：一项与皮肤镜相关的免疫组织化学研究
Am J Dermatopathol. 2022 Apr 1;44(4):254-256. doi: 10.1097/DAD.0000000000002115.
4
Frontal fibrosing alopecia in men: A multicenter study of 39 patients.男性额部纤维性秃发：39例患者的多中心研究。
J Am Acad Dermatol. 2022 Feb;86(2):481-484. doi: 10.1016/j.jaad.2021.09.033. Epub 2021 Sep 22.
5
Hypopigmentation of the Eyebrows in Frontal Fibrosing Alopecia.额部纤维性秃发中眉毛色素减退
Skin Appendage Disord. 2021 Apr;7(3):243-245. doi: 10.1159/000512866. Epub 2021 Feb 10.
6
Sensitization to benzyl salicylate and other allergens in patients with frontal fibrosing alopecia.患有额部纤维性脱发症患者对苯甲酸苄酯和其他变应原的致敏作用。
Contact Dermatitis. 2021 Jun;84(6):423-430. doi: 10.1111/cod.13763. Epub 2021 Jan 26.
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Frontal Fibrosing Alopecia Associated with Lichen Planus Pigmentosus: Not Only in Dark Phototypes.与色素性扁平苔藓相关的额部纤维性秃发：不仅见于深肤色类型。
Skin Appendage Disord. 2020 Jul;6(4):235-239. doi: 10.1159/000507379. Epub 2020 Jun 4.
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Clinical characteristics, trichoscopy, histopathology and treatment outcomes of frontal fibrosing alopecia in an Asian population: A retro-prospective cohort study.亚洲人群中额部纤维化性秃发的临床特征、毛发镜检查、组织病理学及治疗结果：一项回顾性队列研究
J Dermatol. 2020 Nov;47(11):1301-1311. doi: 10.1111/1346-8138.15517. Epub 2020 Jul 24.
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Dermatol Ther. 2020 Jul;33(4):e13560. doi: 10.1111/dth.13560. Epub 2020 Jun 4.