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额部纤维性秃发中的面部丘疹:毳毛毛囊受累的证据。

Facial papules in frontal fibrosing alopecia: evidence of vellus follicle involvement.

作者信息

Donati Aline, Molina Luciana, Doche Isabella, Valente Neusa S, Romiti Ricardo

机构信息

Department of Dermatology, University of São Paulo, São Paulo 05403-900, Brazil.

出版信息

Arch Dermatol. 2011 Dec;147(12):1424-7. doi: 10.1001/archdermatol.2011.321.

Abstract

BACKGROUND

Frontal fibrosing alopecia is considered a particular clinical form of lichen planopilaris that primarily involves the scalp hair over the frontal hairline. Concomitant involvement of vellus at different body sites has recently been reported. To our knowledge, this is the first report on the involvement of facial vellus by effects of the inflammatory process. Unlike the usual noninflammatory clinical presentation of vellus involvement over other body areas, facial vellus involvement can lead to surface changes that may be recognized both by patients and dermatologists.

OBSERVATIONS

Four patients with typical clinical features of frontal fibrosing alopecia presented with noninflammatory follicular papules over the face, most often inside the temporal area, and described as "roughness" by the patients. Histologic samples showed lichen planopilaris features involving the facial vellus.

CONCLUSIONS

The new concept of frontal fibrosing alopecia as a generalized disease is important for treatment planning and research. Dermatologists must learn to recognize facial surface changes and discuss these with the patients, who may attribute this roughness to aging or hormonal changes associated with menopause. Further studies are needed to determine the prevalence of this involvement in patients with frontal fibrosing alopecia.

摘要

背景

额部纤维性秃发被认为是扁平苔藓性毛发角化病的一种特殊临床类型,主要累及额发际线处的头皮毛发。最近有报道称不同身体部位的毳毛也会同时受累。据我们所知,这是关于炎症过程影响面部毳毛的首次报道。与其他身体部位毳毛受累时通常的非炎症临床表现不同,面部毳毛受累会导致表面变化,患者和皮肤科医生都能察觉到。

观察结果

4例具有典型额部纤维性秃发临床特征的患者面部出现非炎症性毛囊丘疹,最常见于颞部区域内,患者描述为“粗糙感”。组织学样本显示扁平苔藓性毛发角化病累及面部毳毛。

结论

将额部纤维性秃发视为一种全身性疾病的新概念对于治疗规划和研究很重要。皮肤科医生必须学会识别面部表面变化并与患者讨论,患者可能将这种粗糙感归因于衰老或与绝经相关的激素变化。需要进一步研究以确定这种受累情况在额部纤维性秃发患者中的发生率。

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