Department of Medicine, University of North Carolina, Rex Vascular Specialists UNC Health, 4414 Lake Boone Trail, Suite 505, Chapel Hill, NC, 27607, USA.
Curr Cardiol Rep. 2024 Nov;26(11):1241-1247. doi: 10.1007/s11886-024-02119-1. Epub 2024 Aug 31.
This review will focus on comprehensive evaluation of chronic venous insufficiency (CVI), nuances in diagnostic testing and advances in medical therapies to provide improvement in patient specific outcomes.
Chronic venous insufficiency of the lower extremities represents an often underrecognized source of morbidity. Comprehensive evaluation focuses on personal and family history of deep vein thrombosis and varicose veins. Diagnostic testing is initially with a thorough duplex ultrasound, but advanced imaging with CT scan and MRV may be indicated in selected patients who might benefit from more invasive intervention. Compression therapy, wraps and garments, remains the mainstay of conservative therapy for patients with CVI. In addition, there is renewed interest in lifestyle and nutritional supplements, most commonly micronized purified flavanoid fraction (MPFF), in relieving symptoms and preventing morbidity. A holistic approach to patients with CVI provides the best opportunity for enduring improvement in quality of life.
本篇综述将重点关注慢性静脉功能不全(CVI)的全面评估、诊断检测的细微差别以及医学治疗的进展,以改善患者的具体预后。
下肢慢性静脉功能不全是一种经常被低估的发病率来源。全面评估侧重于深静脉血栓形成和静脉曲张的个人和家族病史。初始诊断测试是进行彻底的双功能超声检查,但对于可能受益于更具侵入性干预的特定患者,可能需要进行 CT 扫描和 MRV 等高级影像学检查。对于 CVI 患者,加压治疗、包扎和衣物仍然是保守治疗的主要方法。此外,人们对生活方式和营养补充剂,特别是微粉化纯化黄酮类化合物(MPFF),在缓解症状和预防发病方面的作用重新产生了兴趣。对 CVI 患者采用整体方法可最大程度地提高生活质量的持久改善。