College of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China.
Institute of Analytical Technology and Smart Instruments and Colleague of Environment and Public Healthy, Xiamen Huaxia University, Xiamen 361024, China.
Food Chem. 2025 Jan 1;462:141007. doi: 10.1016/j.foodchem.2024.141007. Epub 2024 Aug 26.
In this study, covalent organic frameworks (COFs) were grown in situ on magnetic nitrogen-doped graphene foam (MNGF), and the resulting composite of COFs-modified MNGF (MNC) was wrapped by molecularly imprinted polymers (MNC@MIPs) for specifically capturing SAs. A magnetic solid phase extraction (MSPE) method for SAs was established using MNC@MIPs with good magnetic responsiveness. The adsorption performance of MNC@MIPs was superior to that of non-molecularly imprinted polymers (MNC@NIPs), with shorter adsorption/desorption time and higher imprinting factors. A high-efficiency SAs analytical method was developed by fusing HPLC and MNC@MIPs-based MSPE. This approach provides excellent precision, a low detection limit, and wide linearity. By analyzing fish samples, the feasibility of the approach was confirmed, with SAs recoveries and relative standard deviations in spiked samples in the ranges of 77.2-112.7 % and 2.0-7.2 %, respectively. This study demonstrated the potential use of MNC@MIPs-based MSPE for efficient extraction and quantitation of trace hazards in food.
在这项研究中，共价有机框架（COFs）原位生长在磁性氮掺杂石墨烯泡沫（MNGF）上，所得的 COFs 修饰的 MNGF（MNC）复合材料被分子印迹聚合物（MNC@MIPs）包裹，用于特异性捕获 SAs。使用具有良好磁响应性的 MNC@MIPs 建立了用于 SAs 的磁固相萃取（MSPE）方法。MNC@MIPs 的吸附性能优于非分子印迹聚合物（MNC@NIPs），具有更短的吸附/解吸时间和更高的印迹因子。通过将 HPLC 与基于 MNC@MIPs 的 MSPE 融合，开发了一种高效的 SAs 分析方法。该方法具有出色的精密度、低检测限和较宽的线性范围。通过分析鱼类样品，证实了该方法的可行性，加标样品中 SAs 的回收率和相对标准偏差分别在 77.2-112.7%和 2.0-7.2%范围内。本研究证明了基于 MNC@MIPs 的 MSPE 用于从食品中有效提取和定量痕量危害物的潜力。
