Escherichia coli thymine auxotrophs suppressible by carbon dioxide.
作者信息
Dale J W, Smith J T
出版信息
J Gen Microbiol. 1985 Apr;131(4):935-8. doi: 10.1099/00221287-131-4-935.
PMID:3921661
Abstract
Two independently-isolated thymine-requiring mutant strains of Escherichia coli were found to possess an unusual phenotype: in the presence of CO2, growth was independent of thymine. The two strains showed different profiles of temperature sensitivity. Glycine, serine and methionine were unable to relieve the thymine-dependence. Both strains were susceptible to trimethoprim under conditions where they were thymine-independent. The results are consistent with the occurrence of partial defects in thymidylate synthase.
摘要
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