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扁平苔藓与肝脏疾病:二者关联有多紧密?

Lichen planus and liver disease: how strong is the association?

作者信息

Scully C, Potts A J, Hamburger J, Wiesenfeld D, McKee J I, el Kom M

出版信息

J Oral Pathol. 1985 Mar;14(3):224-6. doi: 10.1111/j.1600-0714.1985.tb00485.x.

DOI:10.1111/j.1600-0714.1985.tb00485.x
PMID:3921677
Abstract

One hundred and thirteen patients with histologically confirmed oral lichen planus, from three stomatology clinics, were examined for evidence of liver disease. No patient had clinical evidence of liver disease. Nine patients (7.9%) had a raised serum concentration of a single enzyme; 6 patients had raised gamma-glutamyl transpeptidase, 2 had raised alkaline phosphatase, and 1 had raised aspartate transaminase levels. No patient had serum auto-antibodies suggestive of primary biliary cirrhosis or chronic active hepatitis. Most patients presenting with oral lichen planus are unlikely to have liver disease.

摘要

来自三家口腔诊所的113例经组织学确诊为口腔扁平苔藓的患者接受了肝病检查。没有患者有肝病的临床证据。9例患者(7.9%)有一种酶的血清浓度升高;6例患者γ-谷氨酰转肽酶升高,2例碱性磷酸酶升高,1例天冬氨酸转氨酶水平升高。没有患者有提示原发性胆汁性肝硬化或慢性活动性肝炎的血清自身抗体。大多数患口腔扁平苔藓的患者不太可能患有肝病。

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1
Lichen planus and liver disease: how strong is the association?扁平苔藓与肝脏疾病:二者关联有多紧密?
J Oral Pathol. 1985 Mar;14(3):224-6. doi: 10.1111/j.1600-0714.1985.tb00485.x.
2
Incidence of liver disease in chronic lichen planus of the mouth.口腔慢性扁平苔藓患者的肝脏疾病发病率
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[Oral lichen planus and liver pathology. I. The prevalence of liver damage in a case load of 96 patients with oral lichen planus].[口腔扁平苔藓与肝脏病理学。I. 96例口腔扁平苔藓患者肝脏损害的患病率]
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Lichen planus and liver diseases: a multicentre case-control study. Gruppo Italiano Studi Epidemiologici in Dermatologia (GISED).扁平苔藓与肝脏疾病:一项多中心病例对照研究。意大利皮肤病流行病学研究组(GISED)。
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Liver abnormalities in patients with lichen planus. A retrospective case-control study.扁平苔藓患者的肝脏异常。一项回顾性病例对照研究。
J Am Acad Dermatol. 1984 Oct;11(4 Pt 1):609-15. doi: 10.1016/s0190-9622(84)70215-5.

引用本文的文献

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Oral lichen planus - Review on etiopathogenesis.口腔扁平苔藓——病因发病机制综述
Natl J Maxillofac Surg. 2011 Jan;2(1):15-6. doi: 10.4103/0975-5950.85847.