Department of Orthopedics, Orthopaedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Model Worker and Craftsman Talent Innovation Workshop of Sichuan province, Chengdu, China.
Bone Joint J. 2024 Sep 1;106-B(9):1000-1007. doi: 10.1302/0301-620X.106B9.BJJ-2024-0109.R1.
Endoprosthetic reconstruction following distal femur tumour resection has been widely advocated. In this paper, we present the design of an uncemented endoprosthesis system featuring a short, curved stem, with the goal of enhancing long-term survivorship and functional outcomes.
This study involved patients who underwent implantation of an uncemented distal femoral endoprosthesis with a short and curved stem between 2014 and 2019. Functional outcomes were assessed using the 1993 version of the Musculoskeletal Tumour Society (MSTS-93) score. Additionally, we quantified five types of complications and assessed osseointegration radiologically. The survivorship of the endoprosthesis was evaluated according to two endpoints. A total of 134 patients with a median age of 26 years (IQR 16 to 41) were included in our study. The median follow-up time was 61 months (IQR 56 to 76), and the median functional MSTS-93 was 83% (IQR 73 to 91) postoperatively.
Overall, 21 patients (16%) encountered complications, and the rate of aseptic loosening was 7% (9/134). The survival rate up to 8.5 years was 93% for aseptic loosening as the endpoint, and 88% for any reason as the endpoint, retrospectively.
The use of an uncemented distal femoral endoprosthesis with a short, curved stem demonstrated a low incidence of aseptic loosening and achieved long-term survivorship of up to nine years. Meanwhile, aseptic loosening typically occurs in the early stage postoperatively.
广泛提倡在股骨远端肿瘤切除后进行假体重建。本文介绍了一种带有短而弯曲柄的非骨水泥假体系统的设计,目的是提高长期存活率和功能结果。
本研究纳入了 2014 年至 2019 年间接受非骨水泥股骨远端假体植入术的患者,假体带有短而弯曲的柄。采用 1993 年版肌肉骨骼肿瘤学会(MSTS-93)评分评估功能结果。此外,我们量化了五种类型的并发症,并进行了影像学评估骨整合情况。假体的存活率根据两个终点进行评估。共纳入 134 例患者,中位年龄 26 岁(IQR 16 至 41)。中位随访时间为 61 个月(IQR 56 至 76),术后中位 MSTS-93 功能评分为 83%(IQR 73 至 91)。
总体而言,21 例(16%)患者发生并发症,无菌性松动率为 7%(9/134)。以无菌性松动为终点,8.5 年的生存率为 93%,以任何原因作为终点,88%的生存率为 88%,为回顾性分析。
使用带有短而弯曲柄的非骨水泥股骨远端假体,无菌性松动发生率低,可实现长达 9 年的长期存活率。同时,无菌性松动通常发生在术后早期。