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无骨水泥短弯柄远端股骨假体治疗骨肿瘤患者的生存情况、并发症和功能结局。

Survivorship, complications, and functional outcomes of uncemented distal femoral endoprosthesis with short, curved stem for patients with bone tumours.

机构信息

Department of Orthopedics, Orthopaedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.

Model Worker and Craftsman Talent Innovation Workshop of Sichuan province, Chengdu, China.

出版信息

Bone Joint J. 2024 Sep 1;106-B(9):1000-1007. doi: 10.1302/0301-620X.106B9.BJJ-2024-0109.R1.

Abstract

AIMS

Endoprosthetic reconstruction following distal femur tumour resection has been widely advocated. In this paper, we present the design of an uncemented endoprosthesis system featuring a short, curved stem, with the goal of enhancing long-term survivorship and functional outcomes.

METHODS

This study involved patients who underwent implantation of an uncemented distal femoral endoprosthesis with a short and curved stem between 2014 and 2019. Functional outcomes were assessed using the 1993 version of the Musculoskeletal Tumour Society (MSTS-93) score. Additionally, we quantified five types of complications and assessed osseointegration radiologically. The survivorship of the endoprosthesis was evaluated according to two endpoints. A total of 134 patients with a median age of 26 years (IQR 16 to 41) were included in our study. The median follow-up time was 61 months (IQR 56 to 76), and the median functional MSTS-93 was 83% (IQR 73 to 91) postoperatively.

RESULTS

Overall, 21 patients (16%) encountered complications, and the rate of aseptic loosening was 7% (9/134). The survival rate up to 8.5 years was 93% for aseptic loosening as the endpoint, and 88% for any reason as the endpoint, retrospectively.

CONCLUSION

The use of an uncemented distal femoral endoprosthesis with a short, curved stem demonstrated a low incidence of aseptic loosening and achieved long-term survivorship of up to nine years. Meanwhile, aseptic loosening typically occurs in the early stage postoperatively.

摘要

目的

广泛提倡在股骨远端肿瘤切除后进行假体重建。本文介绍了一种带有短而弯曲柄的非骨水泥假体系统的设计,目的是提高长期存活率和功能结果。

方法

本研究纳入了 2014 年至 2019 年间接受非骨水泥股骨远端假体植入术的患者,假体带有短而弯曲的柄。采用 1993 年版肌肉骨骼肿瘤学会(MSTS-93)评分评估功能结果。此外,我们量化了五种类型的并发症,并进行了影像学评估骨整合情况。假体的存活率根据两个终点进行评估。共纳入 134 例患者,中位年龄 26 岁(IQR 16 至 41)。中位随访时间为 61 个月(IQR 56 至 76),术后中位 MSTS-93 功能评分为 83%(IQR 73 至 91)。

结果

总体而言,21 例(16%)患者发生并发症,无菌性松动率为 7%(9/134)。以无菌性松动为终点,8.5 年的生存率为 93%,以任何原因作为终点,88%的生存率为 88%,为回顾性分析。

结论

使用带有短而弯曲柄的非骨水泥股骨远端假体,无菌性松动发生率低,可实现长达 9 年的长期存活率。同时,无菌性松动通常发生在术后早期。

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