Saul R F, Hamburger H A, Selhorst J B
JAMA. 1985 May 17;253(19):2869-70.
Three patients were initially seen with headache, blurred vision, and papilledema while taking lithium carbonate for their respective bipolar affective disorder. A diagnosis of pseudotumor cerebri was made in each case when a thorough evaluation revealed only elevated intracranial pressure. Two of the patients had complete resolution of their symptoms and papilledema after discontinuing use of the drug. Increased intracranial pressure with papilledema persisted in the third patient when she failed to adjust psychiatrically, necessitating continuance of the lithium carbonate therapy. A history of lithium carbonate ingestion should be sought in patients with the syndrome of pseudotumor cerebri. All patients receiving this drug should have a regular funduscopic examination.
三名患者在服用碳酸锂治疗各自的双相情感障碍时，最初出现头痛、视力模糊和视乳头水肿。在全面评估仅发现颅内压升高后，每例均诊断为假性脑瘤。两名患者停药后症状和视乳头水肿完全消退。第三名患者因精神状态未调整，颅内压升高和视乳头水肿持续存在，因此需要继续碳酸锂治疗。对于假性脑瘤综合征患者，应询问碳酸锂摄入史。所有接受该药物治疗的患者均应定期进行眼底检查。
