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Why is single sample rule out of non-ST elevation myocardial infarction using high-sensitivity cardiac troponin T safe when analytical imprecision is so high? A joint statistical and clinical demonstration.

作者信息

Hatherley James Daniel, Miller Guy, Collinson Paul, Shantsila Eduard, Fearon Hannah, Lambert Angela, Khand Yusuf, Khand Aleem

机构信息

4595 Liverpool University Hospitals NHS Foundation Trust , Cardiology Department, Liverpool, UK.

University of Liverpool, Faculty of Health and Life Sciences, Liverpool, UK.

出版信息

Clin Chem Lab Med. 2024 Sep 2;63(3):e63-e66. doi: 10.1515/cclm-2024-0647. Print 2025 Feb 25.

DOI:10.1515/cclm-2024-0647
PMID:39217629
Abstract
摘要

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Why is single sample rule out of non-ST elevation myocardial infarction using high-sensitivity cardiac troponin T safe when analytical imprecision is so high? A joint statistical and clinical demonstration.当分析不精密度如此之高时，为何使用高敏心肌肌钙蛋白T进行单样本排除非ST段抬高型心肌梗死是安全的？一项统计学与临床联合论证。
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引用本文的文献

1
High sensitivity cardiac troponin assays, rapid myocardial infarction rule-out algorithms, and assay performance.高敏心肌肌钙蛋白检测、急性心肌梗死快速排除算法及检测性能。
Clin Chem Lab Med. 2025 Jan 10;63(3):462-464. doi: 10.1515/cclm-2025-0013. Print 2025 Feb 25.