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High sensitivity cardiac troponin assays, rapid myocardial infarction rule-out algorithms, and assay performance.

作者信息

Lackner Karl J

机构信息

Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

出版信息

Clin Chem Lab Med. 2025 Jan 10;63(3):462-464. doi: 10.1515/cclm-2025-0013. Print 2025 Feb 25.

DOI:10.1515/cclm-2025-0013
PMID:39786539
Abstract
摘要

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High sensitivity cardiac troponin assays, rapid myocardial infarction rule-out algorithms, and assay performance.高敏心肌肌钙蛋白检测、急性心肌梗死快速排除算法及检测性能。
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4
Serial high-sensitivity cardiac troponin T measurements to rule out acute myocardial infarction and a single high baseline measurement for swift rule-in: A systematic review and meta-analysis.连续检测高敏心肌肌钙蛋白 T 以排除急性心肌梗死和单次高基线检测以快速确诊：系统评价和荟萃分析。
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Cardiac Troponin Assays With Improved Analytical Quality: A Trade-Off Between Enhanced Diagnostic Performance and Reduced Long-Term Prognostic Value.心肌肌钙蛋白检测分析质量的改善：提高诊断性能与降低长期预后价值之间的权衡。
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本文引用的文献

1
Impact of high-sensitivity cardiac troponin I assay imprecision on the safety of a single-sample rule-out approach for myocardial infarction.高敏心肌肌钙蛋白I检测不精密度对心肌梗死单样本排除法安全性的影响
Clin Chem Lab Med. 2024 Sep 20;63(3):e59-e62. doi: 10.1515/cclm-2024-1011. Print 2025 Feb 25.
2
Why is single sample rule out of non-ST elevation myocardial infarction using high-sensitivity cardiac troponin T safe when analytical imprecision is so high? A joint statistical and clinical demonstration.当分析不精密度如此之高时，为何使用高敏心肌肌钙蛋白T进行单样本排除非ST段抬高型心肌梗死是安全的？一项统计学与临床联合论证。
Clin Chem Lab Med. 2024 Sep 2;63(3):e63-e66. doi: 10.1515/cclm-2024-0647. Print 2025 Feb 25.
3
Determination of Clinically Acceptable Analytical Variation of Cardiac Troponin at Decision Thresholds.
确定决策界值时肌钙蛋白的临床可接受分析变异。
Clin Chem. 2024 Jul 5;70(7):967-977. doi: 10.1093/clinchem/hvae059.
4
Lower Limits for Reporting High-Sensitivity Cardiac Troponin Assays and Impact of Analytical Performance on Patient Misclassification.报告高敏心肌肌钙蛋白检测的下限值和分析性能对患者误诊的影响。
Clin Chem. 2024 Mar 2;70(3):497-505. doi: 10.1093/clinchem/hvad185.
5
Rapid rule-in and rule-out protocols of acute myocardial infarction using hs-cTnI and hs-cTnT methods.采用高敏心肌肌钙蛋白I（hs-cTnI）和高敏心肌肌钙蛋白T（hs-cTnT）方法对急性心肌梗死进行快速诊断与排除的方案
Clin Chem Lab Med. 2023 Sep 25;62(2):213-217. doi: 10.1515/cclm-2023-1010. Print 2024 Jan 26.
6
2023 ESC Guidelines for the management of acute coronary syndromes.2023年欧洲心脏病学会急性冠状动脉综合征管理指南。
Eur Heart J. 2023 Oct 12;44(38):3720-3826. doi: 10.1093/eurheartj/ehad191.
7
Variability of cardiac troponin levels in normal subjects and in patients with cardiovascular diseases: analytical considerations and clinical relevance.正常受试者和心血管疾病患者中心肌肌钙蛋白水平的变异性：分析考虑和临床相关性。
Clin Chem Lab Med. 2023 Jan 26;61(7):1209-1229. doi: 10.1515/cclm-2022-1285. Print 2023 Jun 27.
8
Diagnostic discrimination of a novel high-sensitivity cardiac troponin I assay and derivation/validation of an assay-specific 0/1h-algorithm.一种新型高敏心肌肌钙蛋白I检测方法的诊断鉴别以及特定检测方法的0/1小时算法的推导/验证
Am Heart J. 2023 Jan;255:58-70. doi: 10.1016/j.ahj.2022.10.007. Epub 2022 Oct 13.
9
Evaluation and Comparison with Other High-Sensitivity Methods of Analytical Performance and Measured Values of a New Laboratory Test for Cardiac Troponin I Assay.一种新型心脏肌钙蛋白 I 检测的分析性能评估及其与其他高灵敏度方法测量值的比较。
J Appl Lab Med. 2021 Sep 1;6(5):1237-1250. doi: 10.1093/jalm/jfab017.
10
Evaluation of reproducibility of the cTnT immunoassay using quality control samples.使用质量控制样本评估肌钙蛋白T免疫测定的可重复性。
Clin Chim Acta. 2019 Aug;495:269-270. doi: 10.1016/j.cca.2019.04.068. Epub 2019 Apr 22.