National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Settsu-city, Osaka, Japan; Tokyo Metropolitan Institute for Geriatrics and Gerontology, Itabashi-city, Tokyo, Japan; Department of Frontier Health Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, Arakawa-city, Tokyo, Japan.
National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Settsu-city, Osaka, Japan; Faculty of Sport Sciences, Waseda University, Tokorozawa-city, Saitama, Japan; Institute of Interdisciplinary Research, Institute for Active Health, Kyoto University of Advanced Science, Kameoka-city, Kyoto, Japan.
J Am Med Dir Assoc. 2024 Nov;25(11):105232. doi: 10.1016/j.jamda.2024.105232. Epub 2024 Aug 30.
Some studies reported a relationship between life-space mobility (LSM) and frailty assessed by physical aspects; however, a more comprehensive discussion of frailty is underdeveloped. In addition, previous studies have focused only on older Euro-American people. Therefore, we aimed to examine LSM-frailty relationships in community-dwelling older Japanese persons using physical and comprehensive frailty indices.
A cross-sectional study.
We used the data of 8898 older adults from a baseline survey of the Kyoto-Kameoka Study in Japan.
The validated life-space assessment (LSA) was used to evaluate LSM and categorized it into quartiles. Two validated indices were used to evaluate frailty: the Kihon Checklist (KCL) and the simple Frailty Screening Index (FSI). Multivariable logistic regression was used to determine the relationships between LSM scores and frailty.
The mean age (SD) of the participants was 73.4 (6.3) years, and 53.3% were women. The mean LSM score of the study participants was 53.0. The prevalence of frailty by KCL and FSI was 40.7% and 16.8%, respectively. Significant differences between LSM score and frailty prevalence were observed [KCL: Q1, reference; Q2, odds ratio (OR) 0.53, 95% CI 0.45-0.62; Q3, OR 0.30, 95% CI 0.25-0.35; Q4: OR 0.22, 95% CI 0.18-0.26, P for trend <.001; FSI: Q1, reference; Q2, OR 0.57, 95% CI 0.48-0.68; Q3: OR 0.38, 95% CI 0.31-0.46; Q4: OR 0.35, 95% CI 0.28-0.42, P for trend <.001]. Similar results were observed when LSM scores were examined at 10-point intervals, with LSM and frailty exhibiting an L-shaped relationship. The LSM score dose-response curve at which the OR for frailty plateaued among older individuals was approximately 81-90 score.
LSM score and frailty prevalence exhibited L-shaped relationships in community-dwelling older persons. This study's findings provide useful data for setting LSM targets for preventing frailty in community-dwelling older persons.
一些研究报告了生活空间移动性（LSM）与身体方面评估的虚弱之间的关系；然而，对虚弱的更全面讨论仍不够充分。此外，以前的研究仅关注老年欧美人。因此，我们旨在使用身体和综合虚弱指数，检查社区居住的日本老年人中 LSM-虚弱的关系。
一项横断面研究。
我们使用了来自日本京都-龟冈研究基线调查的 8898 名老年人的数据。
使用经过验证的生活空间评估（LSA）来评估 LSM，并将其分为四分位。使用两个经过验证的指数来评估虚弱：基本健康检查表（KCL）和简单虚弱筛查指数（FSI）。多变量逻辑回归用于确定 LSM 评分与虚弱之间的关系。
参与者的平均年龄（SD）为 73.4（6.3）岁，53.3%为女性。研究参与者的平均 LSM 评分为 53.0。根据 KCL 和 FSI，虚弱的患病率分别为 40.7%和 16.8%。LSM 评分与虚弱患病率之间存在显著差异[KCL：Q1，参考；Q2，比值比（OR）0.53，95%CI 0.45-0.62；Q3，OR 0.30，95%CI 0.25-0.35；Q4：OR 0.22，95%CI 0.18-0.26，P<0.001；FSI：Q1，参考；Q2，OR 0.57，95%CI 0.48-0.68；Q3：OR 0.38，95%CI 0.31-0.46；Q4：OR 0.35，95%CI 0.28-0.42，P<0.001]。当以 10 分间隔检查 LSM 评分时，也观察到类似的结果，LSM 和虚弱呈 L 形关系。在老年人中，虚弱的 LSM 评分剂量反应曲线中，OR 趋于平稳的分数约为 81-90 分。
社区居住的老年人中，LSM 评分和虚弱患病率呈 L 形关系。本研究结果为确定社区居住的老年人预防虚弱的 LSM 目标提供了有用的数据。
