1Department of Applied Mechanics, Vilnius Gediminas Technical University, Vilnius, Lithuania.
Acta Bioeng Biomech. 2024 Apr 15;26(1):13-22. doi: 10.37190/abb-02392-2024-03. Print 2024 Jun 1.
: This study aimed to evaluate the biomechanical response or load transfer on the osteoporotic L1 vertebra under torsional loading. : To achieve this goal, a numerical model of osteoporotic vertebra in various trabecular bone degenerations was developed and tested. The mechanical behavior of the model was represented taking into account the anisotropic properties of the cancellous bone, which provided a more realistic mechanical picture of the biological subsystem. To ensure the reliability of osteoporotic degradation, the thinning of cortical bone and the appearance of gaps between trabecular bone and cortical bone were also taken into account when creating the models. : Finite element (FE) analysis showed that the deformations of cortical bone thinning and detachment of the cortical bone from the trabecular tissue lead to local instability of the vertebra. As a result, the cortical bone of a vertebra loses its load-bearing capacity, even if the strength limit is not reached. : The results obtained allow us to state that taking into account the thinning of the trabeculae, which creates voids, is extremely important for load-bearing capacity of osteoporotic vertebrae. However, a limitation of this study is the lack of experimental data to ensure consistency with the computer simulation results.
: 本研究旨在评估扭转载荷下骨质疏松 L1 椎体的生物力学响应或载荷传递。: 为了实现这一目标，开发并测试了各种松质骨退化的骨质疏松椎体的数值模型。考虑到松质骨的各向异性特性，该模型的机械行为得到了体现，为生物子系统提供了更真实的力学图像。为了确保骨质疏松退化的可靠性，在创建模型时还考虑了皮质骨变薄和松质骨与皮质骨之间出现间隙的情况。: 有限元（FE）分析表明，皮质骨变薄和皮质骨从松质组织分离的变形导致椎体局部不稳定。结果，即使未达到强度极限，椎体的皮质骨也会失去承载能力。: 研究结果表明，考虑到会产生空洞的小梁变薄非常重要，这对于骨质疏松椎体的承载能力至关重要。然而，本研究的一个限制是缺乏实验数据，无法确保与计算机模拟结果一致。
