与口服妥卡尼相关的意识模糊和偏执。
Confusion and paranoia associated with oral tocainide.
作者信息
Clarke C W, el-Mahdi E O
出版信息
Postgrad Med J. 1985 Jan;61(711):79-81. doi: 10.1136/pgmj.61.711.79.
Abstract
Two middle aged female patients developed hallucinations and severe confusion with paranoid features during oral tocainide administration at recommended dosage levels. Both patients had evidence of impaired renal function. Symptoms were provoked on re-challenge in the first patient. In the second patient the tocainide blood level was higher than the recommended therapeutic range. Both patients reverted to their normal mental state on withdrawal of the drug.
摘要
两名中年女性患者在按推荐剂量口服妥卡尼期间出现幻觉和伴有偏执特征的严重意识模糊。两名患者均有肾功能受损的证据。第一名患者再次用药时症状复发。第二名患者的妥卡尼血药浓度高于推荐治疗范围。两名患者停药后均恢复至正常精神状态。
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