[合成三肽微小促黄体素释放激素及其生物活性]
[Synthetic tripeptide miniluliberin and its biological activity].
作者信息
Babichev V N, Adamskaia E I, Bukiia N G, Shvachkin Iu P, Tikhonov Iu N
出版信息
Probl Endokrinol (Mosk). 1985 Mar-Apr;31(2):47-9.
PMID:3921955
Abstract
The effects of the synthetic decapeptide LH-RH and tripeptide mini LH-RH on LH and FSH secretion were compared. Experiments on ovariectomized female rats receiving estradiol benzoate and progesterone showed that i. v. administration of mini LH-RH produced a stimulating effect on the release of gonadotrophins from the hypophysis. The effects of mini LH-RH were incomparable to those of LH-RH.
摘要
比较了合成十肽促性腺激素释放激素（LH-RH）和三肽微型LH-RH对促黄体生成素（LH）和促卵泡生成素（FSH）分泌的影响。在接受苯甲酸雌二醇和孕酮的去卵巢雌性大鼠身上进行的实验表明，静脉注射微型LH-RH对垂体促性腺激素的释放产生刺激作用。微型LH-RH的作用与LH-RH的作用无法相比。
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