Oikawa Tomoko, Saito Kaori, Kurihara Keiichi, Horikawa Daisuke, Uruno Katsuhiko, Kajiwara Hironori, Ohashi Shuhei, Hotta Masatoshi, Yagi Naoyuki, Kitamura Hideaki, Hasegawa Shinichi, Minamimoto Ryogo
Department of Radiological Physics and Technology, National Center for Global Health and Medicine, Tokyo, Japan.
Department of Radiological Technology, National Cancer Center Hospital East, Chiba, Japan.
Glob Health Med. 2024 Aug 31;6(4):244-250. doi: 10.35772/ghm.2024.01023.
The aim of this study is to estimate eye lens exposure dose when handling radiopharmaceuticals and interacting with patients receiving radiopharmaceuticals, and to verify the usefulness of X-ray protective goggles in mitigating such radiation exposure using phantoms. To evaluate radiation exposure during the handling of radiopharmaceuticals, we employed a fluorescent glass dosimeter to measure the radiation doses associated with Tc, I, I, In, and F at distances of 30 cm and 60 cm, followed by calculation of the 3 mm dose equivalent rate (3DER). We then estimated the dose reduction rates for various scenarios, including the use of syringe shields and X-ray protective goggles with lead equivalences of 0.07, 0.15, 0.75, and 0.88 mmPb, as well as their combined application. X-ray protective goggles with lead equivalence of 0.75 mmPb outperformed those with 0.07 mmPb and 0.15 mmPb, for all radionuclides and at both source distances. X-ray protective goggles with 0.88 mmPb outperformed those with 0.75 mmPb during handling of I and In at a distance of 30 cm. In the remaining scenarios, X-ray protective goggles with 0.88 mmPb resulted in marginal reductions or no discernible additional effects. The overall shielding effect of X-ray protective goggles was less pronounced for 131I and 18F, but the combined use of a syringe shield with X-ray protective goggles with 0.75 or 0.88 mmPb improved the dose reduction rate for all scenarios. In simulating patient care, X-ray protective goggles with 0.88 mmPb demonstrated a dose reduction effect of approximately 50% or more. X-ray protective goggles could reduce the 3DER for the eye lens, and were more effective when combined with a syringe shield. It is valid to use a lead equivalence of 0.88 mmPb to fully harness the protective capabilities of X-ray shielding goggles when dealing with all five types of nuclides in clinical settings.
本研究的目的是估算在处理放射性药物以及与接受放射性药物治疗的患者互动时眼晶状体的暴露剂量,并使用人体模型验证X射线防护眼镜在减轻此类辐射暴露方面的有效性。为了评估处理放射性药物期间的辐射暴露,我们使用荧光玻璃剂量计在30厘米和60厘米的距离测量与锝、碘、铟和氟相关的辐射剂量,随后计算3毫米剂量当量率(3DER)。然后,我们估算了各种情况下的剂量降低率,包括使用铅当量分别为0.07、0.15、0.75和0.88毫米铅的注射器防护套和X射线防护眼镜,以及它们的联合应用。对于所有放射性核素以及在两个源距离处,铅当量为0.75毫米铅的X射线防护眼镜的防护效果优于铅当量为0.07毫米铅和0.15毫米铅的防护眼镜。在30厘米距离处理碘和铟时,铅当量为0.88毫米铅的X射线防护眼镜的防护效果优于铅当量为0.75毫米铅的防护眼镜。在其余情况下,铅当量为0.88毫米铅的X射线防护眼镜导致的剂量降低幅度较小或没有明显的额外效果。X射线防护眼镜对131碘和18氟的总体屏蔽效果不太明显,但将注射器防护套与铅当量为0.75或0.88毫米铅的X射线防护眼镜联合使用可提高所有情况下的剂量降低率。在模拟患者护理时,铅当量为0.88毫米铅的X射线防护眼镜显示出约50%或更高的剂量降低效果。X射线防护眼镜可降低眼晶状体的3DER,与注射器防护套联合使用时更有效。在临床环境中处理所有五种核素时,使用铅当量为0.88毫米铅以充分发挥X射线防护眼镜的防护能力是有效的。