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膝关节骨关节炎患者对骨质疏松症及其预防的认知、态度和行为:一项中国的横断面研究。

Knowledge, Attitudes, and Practices of Patients with Knee Osteoarthritis Regarding Osteoporosis and Its Prevention: A Cross-Sectional Study in China.

作者信息

Wu Yan, Xu Zhenzhen, Dong Jing, Zhang Wenzhong, Li Jing, Ji Hong

机构信息

Department of Nursing, The First Affiliated Hospital of Shandong First Medical University (Shandong Provincial Qianfoshan Hospital), Jinan, Shandong, 250014, People's Republic of China.

School of Nursing, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, 250014, People's Republic of China.

出版信息

Int J Gen Med. 2024 Aug 26;17:3699-3709. doi: 10.2147/IJGM.S471924. eCollection 2024.

Abstract

BACKGROUND

Older age and female sex are risk factors for osteoarthritis and osteoporosis (OP). This study evaluated the knowledge, attitudes, and practices of patients with knee osteoarthritis (KOA) in China regarding OP and its prevention. This cross-sectional, questionnaire-based study enrolled patients with KOA at four grade-A tertiary hospitals in Shandong Province between 1st September and 20th November 2022.

METHODS

The administered questionnaire contained 55 items across four dimensions (demographic information, knowledge, attitude, and practice). Logistic regression analyses were performed to identify factors associated with an overall questionnaire score ≥70% of the maximum possible score. SPSS 26.0 was used for the analyses; P<0.05 was considered significant.

RESULTS

The analysis included 434 participants (261 females). The median knowledge, attitude, and practice scores were 7 (interquartile range: 5-10) (possible range, 0-17 points), 44 (interquartile range: 42-49) (possible range, 11-55 points), and 43 (interquartile range: 38-47) (possible range, 13-65 points), respectively. Multivariable logistic regression indicated that female sex (odds ratio [OR], 2.421; 95% confidence interval [95% CI] 1.558-3.762; <0.001), age 56-65 years-old (OR, 4.222; 95% CI, 1.763-10.109; =0.001 vs ≤55 years-old), age >65 years-old (OR, 4.358; 95% CI, 1.863-10.195; =0.001 vs ≤55 years-old), middle/high/technical secondary school education (OR, 1.853; 95% CI, 1.002-3.428; =0.049 vs primary school or below), and having KOA for 4-5 years (OR, 2.682; 95% CI, 1.412-5.094; =0.003 vs ≤3 years) were independently associated with a high KAP score.

CONCLUSION

There is room for improvement in the knowledge and practices of patients with osteoarthritis in China regarding OP. The findings of this study may facilitate the design and implementation of education programs to increase awareness about OP prevention among patients with KOA.

摘要

背景

高龄和女性是骨关节炎和骨质疏松症(OP)的危险因素。本研究评估了中国膝关节骨关节炎(KOA)患者对OP及其预防的知识、态度和行为。这项基于问卷的横断面研究于2022年9月1日至11月20日在山东省四家三级甲等医院招募了KOA患者。

方法

所发放的问卷包含四个维度(人口统计学信息、知识、态度和行为)的55个项目。进行逻辑回归分析以确定与问卷总分≥最高可能分数70%相关的因素。使用SPSS 26.0进行分析;P<0.05被认为具有统计学意义。

结果

分析纳入434名参与者(261名女性)。知识、态度和行为得分的中位数分别为7分(四分位间距:5 - 10)(可能范围,0 - 17分)、44分(四分位间距:42 - 49)(可能范围,11 - 55分)和43分(四分位间距:38 - 47)(可能范围,13 - 65分)。多变量逻辑回归表明,女性(比值比[OR],2.421;95%置信区间[95%CI] 1.558 - 3.762;<0.001)、年龄56 - 65岁(OR,4.222;95%CI,1.763 - 10.109;与≤55岁相比,P = 0.001)、年龄>65岁(OR,4.358;95%CI,1.863 - 10.195;与≤55岁相比,P = 0.001)、中等/高中/中专学历(OR,1.853;95%CI,1.002 - 3.428;与小学及以下学历相比,P = 0.049)以及患KOA 4 - 5年(OR,2.682;95%CI,1.412 - 5.094;与≤3年相比,P = 0.003)与高KAP得分独立相关。

结论

中国骨关节炎患者在OP知识和行为方面仍有改进空间。本研究结果可能有助于设计和实施教育项目,以提高KOA患者对OP预防的认识。

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Advances in pathogenesis and therapeutic strategies for osteoporosis.骨质疏松症发病机制和治疗策略的研究进展。
Pharmacol Ther. 2022 Sep;237:108168. doi: 10.1016/j.pharmthera.2022.108168. Epub 2022 Mar 10.

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