Federico Seragnoli, Geo Martignoni, Entela Martignoni, Bachmann Silke, Elisa Rabitti, Silvio Cavuto, Zoë Dubus, Louise Penzenstadler, Gabriel Thorens, Joël Billieux, Daniele Zullino
Psychiatry Department Geneva University Hospitals Geneva Switzerland.
Institute of Psychology University of Lausanne Lausanne Switzerland.
Clin Case Rep. 2024 Aug 30;12(9):e9305. doi: 10.1002/ccr3.9305. eCollection 2024 Sep.
This case study describes the feasibility and safety of psychedelic-assisted therapy (PAT) as a home-based intervention for a patient with throat cancer experiencing significant existential distress. The patient tolerated the intervention well. This case supports the feasibility and safety of PAT for patients with life-threatening conditions in a home setting.
Psychedelic-assisted therapy (PAT), as it is practiced today, merges traditional psychotherapeutic techniques with the use of psychedelics such as LSD, psilocybin, or MDMA with the aim of unlocking deeper insights in patients and treating mental conditions that are resistant to other forms of therapy. The present case study describes the safety of PAT as a home-based intervention for a patient with throat cancer experiencing significant existential distress. The patient tolerated the intervention well and was asked to report on measures of anxiety, depression, and distress related to his somatic condition. The observations provided by this clinical case report align with previous findings, suggesting that PAT can be safely applied to potentially provide relief from existential distress in patients with life-threatening conditions. As this is a single-case study, generalizations should be made cautiously. Moreover, placebo effects, expectancy effects, and the natural course of the disease may influence outcomes. Future research should consider controlled trials to ascertain the efficacy and safety of such interventions in diverse settings.
本案例研究描述了迷幻辅助疗法(PAT)作为一种居家干预措施,用于治疗一名患有喉癌且存在严重生存困扰患者的可行性和安全性。该患者对干预耐受良好。此案例支持了PAT在居家环境中用于患有危及生命疾病患者的可行性和安全性。
当今所实施的迷幻辅助疗法(PAT)将传统心理治疗技术与使用诸如麦角酸二乙酰胺(LSD)、裸盖菇素或摇头丸等迷幻剂相结合,旨在使患者获得更深刻的领悟,并治疗对其他形式治疗有抵抗性的精神疾病。本案例研究描述了PAT作为一种居家干预措施,用于治疗一名患有喉癌且存在严重生存困扰患者的安全性。该患者对干预耐受良好,并被要求报告与他躯体状况相关的焦虑、抑郁和困扰程度的指标。这份临床病例报告所提供的观察结果与先前的研究结果一致,表明PAT可以安全应用,有可能缓解患有危及生命疾病患者的生存困扰。由于这是一项单病例研究,应谨慎进行归纳总结。此外,安慰剂效应、期望效应以及疾病的自然病程可能会影响结果。未来的研究应考虑进行对照试验,以确定此类干预措施在不同环境中的疗效和安全性。