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果蝇嘧啶生物合成前三步所编码结构部分的遗传学和细胞学定位。

Genetical and cytological location of the structural parts coding for the first three steps of pyrimidine biosynthesis in Drosophila melanogaster.

作者信息

Jarry B P

出版信息

Mol Gen Genet. 1979 May 4;172(2):199-202. doi: 10.1007/BF00268283.

Abstract

The rudimentary locus (r; X--55.3) of Drosophila melanogaster is shown to contain the structural sequences for the enzymes CPSase, ATCase and DHOase. The enzyme concentration in adult flies is correlated with the number of r+ copies in the genome. The expression of the locus follows the rules of the gene dosage compensation hypothesis when extracts of newly emerged males and females are compared.

摘要

黑腹果蝇的初级位点(r;X-55.3)被证明包含氨甲酰磷酸合成酶(CPSase)、天冬氨酸转氨甲酰酶(ATCase)和二氢乳清酸酶(DHOase)的结构序列。成年果蝇体内的酶浓度与基因组中r+拷贝的数量相关。当比较新羽化的雄性和雌性果蝇提取物时,该位点的表达遵循基因剂量补偿假说的规则。

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