针对Ce-lamin/LMN-1生成一种高度特异性且强效的抗体。
Generation of a highly specific and potent antibody against Ce-lamin/LMN-1.
作者信息
Zahand Adam, Williams Byron, Liu Jun
机构信息
Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
出版信息
MicroPubl Biol. 2024 Aug 15;2024. doi: 10.17912/micropub.biology.001294. eCollection 2024.
High quality antibodies are useful tools for research in cell and developmental biology. We have obtained highly specific and potent guinea pig-derived polyclonal antibodies against Ce-lamin/ LMN-1 . Western blotting experiments using these antibodies demonstrated that maternally loaded Ce-lamin/ LMN-1 protein is very stable, can perdure through embryonic and larval development and remain detectable in homozygous null mutant adults.
高质量抗体是细胞与发育生物学研究的有用工具。我们已获得针对秀丽隐杆线虫核纤层蛋白/Ce-lamin/LMN-1的高度特异性且高效的豚鼠源多克隆抗体。使用这些抗体进行的蛋白质印迹实验表明，母源加载的秀丽隐杆线虫核纤层蛋白/Ce-lamin/LMN-1蛋白非常稳定，能够在胚胎和幼虫发育过程中持续存在，并在纯合缺失突变体成虫中仍可检测到。
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