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疟疾疑似患者血液学参数评估:横断面研究。

Assessment of hematological parameters in malarial suspected patients: Cross sectional study.

作者信息

Khan Tanveer, Khan Abuzar, Khan Anis, Badshah Farhad, Ibáñez-Arancibia Eliana, De Los Ríos-Escalante Patricio R, Maryam Bibi, Noor Nimra, Abdel-Maksoud Mostafa A, El-Tayeb Mohamed A, Hussain Arab

机构信息

Department of Zoology, Bacha Khan University Charsadda, Pakistan.

State Key Laboratory of Animal Biotech Breeding, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China.

出版信息

Parasite Epidemiol Control. 2024 Jul 15;26:e00367. doi: 10.1016/j.parepi.2024.e00367. eCollection 2024 Aug.

DOI:10.1016/j.parepi.2024.e00367
PMID:39220188
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11364049/
Abstract

BACKGROUND

Malaria is a Zoonotic disease, worldwide in distribution and caused by different species of plasmodium. It is a major cause of sickness and mortality in developing countries including Pakistan. This study was carried with the aim to find out the prevalence of malaria and to aware the people about this disease.

METHODS

The study was carried out in district charsadda. 120 blood samples were collected from suspects both male and female, during the period of March 2022 to September 2022 and were analyzed for CBC and for Microscopic examination.

RESULTS

Out of these 120 samples 12(10%) were found positive and 108(90%) were negative. The prevalence of malaria was more in the month of June and July. The infection was high in male (13.3%) as compared to female (6.6%). The prevalence was more in rural areas 8(13.3%) than in urban areas 4(6.6%).

CONCLUSION

The Hemoglobin, Hematocrit, Platelets and Red Blood Cells were found more affected in positive samples as compared to other parameters. The present study will help the malarial control programs to focus on rural areas. The is more common in the study area.

摘要

背景

疟疾是一种人畜共患疾病,分布于全球,由不同种类的疟原虫引起。它是包括巴基斯坦在内的发展中国家疾病和死亡的主要原因。本研究旨在查明疟疾的流行情况,并提高人们对这种疾病的认识。

方法

该研究在查尔萨达县开展。在2022年3月至2022年9月期间,从男性和女性疑似患者身上采集了120份血样,并进行了全血细胞计数和显微镜检查分析。

结果

在这120份样本中,12份(10%)呈阳性,108份(90%)呈阴性。疟疾在6月和7月的患病率更高。男性感染率(13.3%)高于女性(6.6%)。农村地区的患病率(8例,13.3%)高于城市地区(4例,6.6%)。

结论

与其他参数相比,阳性样本中的血红蛋白、血细胞比容、血小板和红细胞受影响更大。本研究将有助于疟疾防控项目关注农村地区。在研究区域[此处原文“the”后缺失内容]更为常见。

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2
Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites.整合蛋白质组学和生物信息学预测使疟原虫中的质体蛋白组具有高度可信度。
PLoS Biol. 2018 Sep 13;16(9):e2005895. doi: 10.1371/journal.pbio.2005895. eCollection 2018 Sep.
3
Effect of malarial infection on haematological parameters in population near Thailand-Myanmar border.疟疾感染对泰国-缅甸边境附近人群血液学参数的影响。
Malar J. 2014 Jun 5;13:218. doi: 10.1186/1475-2875-13-218.
4
Prevalence and distribution of human Plasmodium infection in Pakistan.巴基斯坦人体疟原虫感染的流行状况和分布。
Malar J. 2013 Aug 28;12:297. doi: 10.1186/1475-2875-12-297.
5
Plasmodium knowlesi: a malaria parasite of monkeys and humans.疟原虫 knowlesi:一种猴子和人类的疟疾寄生虫。
Annu Rev Entomol. 2012;57:107-21. doi: 10.1146/annurev-ento-121510-133540.
6
Mortality in sickle cell anemia in Africa: a prospective cohort study in Tanzania.非洲镰状细胞贫血的死亡率:坦桑尼亚的一项前瞻性队列研究。
PLoS One. 2011 Feb 16;6(2):e14699. doi: 10.1371/journal.pone.0014699.
7
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Malar J. 2010 Apr 23;9:112. doi: 10.1186/1475-2875-9-112.
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