疟原虫 knowlesi：一种猴子和人类的疟疾寄生虫。

Plasmodium knowlesi: a malaria parasite of monkeys and humans.

机构信息

Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.

出版信息

Annu Rev Entomol. 2012;57:107-21. doi: 10.1146/annurev-ento-121510-133540.

DOI:10.1146/annurev-ento-121510-133540

PMID:22149265

Abstract

Plasmodium knowlesi is a malaria parasite of monkeys of Southeast Asia that is transmitted by mosquitoes of the Anopheles leucosphyrus group. Humans are frequently infected with this parasite and misdiagnosed as being infected with Plasmodium malariae. The parasite was a major monkey animal model for developing antimalarial vaccines and investigations of the biology of parasite invasion. P. knowlesi is the first monkey malaria parasite genome to be sequenced and annotated.

摘要

疟原虫 knowlesi 是东南亚猴子的一种疟疾寄生虫，由按蚊属 leucosphyrus 组的蚊子传播。人类经常被这种寄生虫感染，并被误诊为感染疟原虫 malariae。该寄生虫是开发抗疟疫苗和研究寄生虫入侵生物学的主要猴子动物模型。P. knowlesi 是第一个测序和注释的猴子疟原虫基因组。