van Bergen Rick, Sun Leshan, Pandey Prabodh Kumar, Wang Siqi, Bjegovic Kristina, Gonzalez Gilberto, Chen Yong, Lopata Richard, Xiang Liangzhong
PULS/e lab Eindhoven, Department of Biomedical Engineering, Eindhoven University of Technology, The Netherlands.
Department of Biomedical Engineering, University of California Irvine, Irvine, CA 92617.
IEEE Trans Radiat Plasma Med Sci. 2024 Jan;8(1):76-87. doi: 10.1109/trpms.2023.3314339. Epub 2023 Sep 12.
Radiation-induced acoustics (RIA) shows promise in advancing radiological imaging and radiotherapy dosimetry methods. However, RIA signals often require extensive averaging to achieve reasonable signal-to-noise ratios, which increases patient radiation exposure and limits real-time applications. Therefore, this paper proposes a discrete wavelet transform (DWT) based filtering approach to denoise the RIA signals and avoid extensive averaging. The algorithm was benchmarked against low-pass filters and tested on various types of RIA sources, including low-energy X-rays, high-energy X-rays, and protons. The proposed method significantly reduced the required averages (1000 times less averaging for low-energy X-ray RIA, 32 times less averaging for high-energy X-ray RIA, and 4 times less averaging for proton RIA) and demonstrated robustness in filtering signals from different sources of radiation. The coif5 wavelet in conjunction with the sqtwolog threshold selection algorithm yielded the best results. The proposed DWT filtering method enables high-quality, automated, and robust filtering of RIA signals, with a performance similar to low-pass filtering, aiding in the clinical translation of radiation-based acoustic imaging for radiology and radiation oncology.
辐射诱导声学(RIA)在推进放射成像和放射治疗剂量测定方法方面显示出前景。然而,RIA信号通常需要大量平均才能获得合理的信噪比,这增加了患者的辐射暴露并限制了实时应用。因此,本文提出一种基于离散小波变换(DWT)的滤波方法来对RIA信号进行去噪并避免大量平均。该算法与低通滤波器进行了基准测试,并在各种类型的RIA源上进行了测试,包括低能X射线、高能X射线和质子。所提出的方法显著减少了所需的平均次数(低能X射线RIA所需平均次数减少1000倍,高能X射线RIA减少32倍,质子RIA减少4倍),并在对来自不同辐射源的信号进行滤波时表现出稳健性。coif5小波与sqtwolog阈值选择算法相结合产生了最佳结果。所提出的DWT滤波方法能够对RIA信号进行高质量、自动化且稳健的滤波,其性能与低通滤波相似,有助于基于辐射的声学成像在放射学和放射肿瘤学中的临床转化。