de Almeida Nathália Alves Araujo, Pimenta Yan Cardoso, de Oliveira Bonfim Flavia Freitas, de Almeida Nicole Carolina Araujo, Leite José Paulo Gagliardi, Olivares Olivares Alberto Ignacio, Nordgren Johan, de Moraes Marcia Terezinha Baroni
Laboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Fiocruz, Rio de Janeiro, RJ, Brazil.
CNPq/Decit/SCTIE/MS, nº 49/2022, Brazil.
Heliyon. 2024 Aug 3;10(16):e35463. doi: 10.1016/j.heliyon.2024.e35463. eCollection 2024 Aug 30.
Worldwide, approximately one fifth of all cases of diarrhea are associated with norovirus, mainly in children, with a defined seasonality in temperate climates, but seasonal dynamics are less known in tropical climates. The objective was to investigate the impact of external clinical, epidemiological, and climatic factors on norovirus detection rates in samples from children under 5 years of age from Roraima, the Amazon region of Brazil. A total of 941 samples were included. According to climatic factors, we observed correlations between external climatic factors and weekly positivity rates, where temperature (P = 0.002), relative humidity (P = 0.0005), absolute humidity (P < 0.0001) and wind speed had the strongest effect (P = 0.0006). The Brazilian Amazon region presents a typical and favorable scenario for the persistence, expansion, and distribution of viral gastroenteritis.
This study is important as it will serve as a basis for studies carried out in Brazil and Latin American countries on the epidemiological importance, seasonality, climate change, antigenic diversity, among other factors in the circulation of gastroenteric virus.
在全球范围内，约五分之一的腹泻病例与诺如病毒有关，主要发生在儿童中，在温带气候中有明确的季节性，但在热带气候中季节性动态情况了解较少。目的是调查外部临床、流行病学和气候因素对来自巴西亚马逊地区罗赖马州5岁以下儿童样本中诺如病毒检测率的影响。共纳入941份样本。根据气候因素，我们观察到外部气候因素与每周阳性率之间存在相关性，其中温度（P = 0.002）、相对湿度（P = 0.0005）、绝对湿度（P < 0.0001）和风速的影响最为显著（P = 0.0006）。巴西亚马逊地区为病毒性肠胃炎的持续存在、传播和扩散提供了一个典型且有利的环境。
本研究具有重要意义，因为它将为巴西和拉丁美洲国家开展的关于肠道病毒传播中的流行病学重要性、季节性、气候变化、抗原多样性等其他因素的研究提供基础。
