Iñiguez-Moreno Maricarmen, Santiesteban-Romero Berenice, Melchor-Martínez Elda M, Parra-Saldívar Roberto, González-González Reyna Berenice
Tecnologico de Monterrey, School of Engineering and Sciences, Monterrey 64849, Mexico.
Tecnologico de Monterrey, Institute of Advanced Materials for Sustainable Manufacturing, Monterrey 64849, Mexico.
MethodsX. 2024 Aug 5;13:102892. doi: 10.1016/j.mex.2024.102892. eCollection 2024 Dec.
Waste from the fishing industry is disposed of in soils and oceans, causing environmental damage. However, it is also a source of valuable compounds such as chitin. Although chitin is the second most abundant polymer in nature, its use in industry is limited due to the lack of standardized and scalable extraction methods and its poor solubility. The deacetylation process increases its potential applications by enabling the recovery of chitosan, which is soluble in dilute acidic solutions. Chitosan is a polymer of great importance due to its biocompatible and bioactive properties, which include antimicrobial and antioxidant capabilities. Chitin extraction and its deacetylation to obtain chitosan are typically performed using chemical processes that involve large amounts of strongly acidic and alkaline solutions. To reduce the environmental impact of this process, extraction methods based on biotechnological tools, such as fermentation and chitin deacetylase, as well as emerging technologies, have been proposed. These extraction methods have demonstrated the potential to reduce or even avoid using strong solvents and shorten extraction time, thereby reducing costs. Nevertheless, it is important to address existing gaps in this area, such as the requirements for large-scale implementation and the determination of the stoichiometric ratios for each process. This review highlights the use of biotechnological tools and emerging technologies for chitin extraction and chitosan production. These approaches truly minimize environmental impact, reduce the use of strong solvents, and shorten extraction time. They are a reliable alternative to fishery waste valorization, lowering costs; however, addressing the critical gaps for their large-scale implementation remains challenging.
渔业废弃物被排放到土壤和海洋中,造成环境破坏。然而,它也是几丁质等有价值化合物的来源。尽管几丁质是自然界中第二丰富的聚合物,但由于缺乏标准化和可扩展的提取方法以及其溶解性差,其在工业中的应用受到限制。脱乙酰化过程通过回收可溶于稀酸性溶液的壳聚糖增加了其潜在应用。壳聚糖由于其生物相容性和生物活性特性(包括抗菌和抗氧化能力)而成为一种非常重要的聚合物。几丁质提取及其脱乙酰化以获得壳聚糖通常使用涉及大量强酸性和碱性溶液的化学过程来进行。为了减少该过程对环境的影响,已经提出了基于生物技术工具(如发酵和几丁质脱乙酰酶)以及新兴技术的提取方法。这些提取方法已显示出减少甚至避免使用强溶剂并缩短提取时间的潜力,从而降低成本。然而,解决该领域现有的差距很重要,例如大规模实施的要求以及每个过程化学计量比的确定。本综述强调了使用生物技术工具和新兴技术进行几丁质提取和壳聚糖生产。这些方法真正将环境影响降至最低,减少了强溶剂的使用,并缩短了提取时间。它们是渔业废弃物增值利用的可靠替代方案,可以降低成本;然而,解决其大规模实施的关键差距仍然具有挑战性。