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无菌性脾脓肿伴Sweet综合征作为新发克罗恩病的肠外表现

Aseptic Splenic Abscesses With Concomitant Sweet Syndrome as Extraintestinal Manifestations of New-Onset Crohn's Disease.

作者信息

McGrath Mary, Geng Calvin, Rainho Anthony, Figueroa Esteban

机构信息

Department of Internal Medicine, University of Virginia Health, Charlottesville, VA.

Division of Gastroenterology and Hepatology, University of Virginia Health, Charlottesville, VA.

出版信息

ACG Case Rep J. 2024 Aug 29;11(9):e01464. doi: 10.14309/crj.0000000000001464. eCollection 2024 Sep.

Abstract

Splenic abscesses are typically infectious in nature but have rarely been reported as an extraintestinal manifestation of inflammatory bowel disease, particularly of Crohn's disease. In the United States, reported cases are even more scarce. We present a case of aseptic splenic abscess with concomitant Sweet syndrome in a middle-aged woman with newly diagnosed Crohn's disease. Extensive workup was required to reach final diagnosis, and she rapidly improved with corticosteroid therapy and has been maintained on risankizumab. We aim to contribute to limited data and heighten clinician awareness of these atypical extraintestinal manifestations.

摘要

脾脓肿通常具有感染性,但作为炎症性肠病,尤其是克罗恩病的肠外表现却鲜有报道。在美国,报道的病例更为稀少。我们报告一例新诊断为克罗恩病的中年女性患者,其患有无菌性脾脓肿并伴有Sweet综合征。为明确最终诊断需要进行广泛的检查,她接受皮质类固醇治疗后迅速好转,并一直使用司库奇尤单抗维持治疗。我们旨在为有限的数据提供补充,并提高临床医生对这些非典型肠外表现的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8350/11361625/132be754a4ae/ac9-11-e01464-g001.jpg

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