Guerra Toro Hector I, Jaramillo Arturo P, Caceres Valeria M
General Practice, Pontificia Universidad Catolica del Ecuador, Quito, ECU.
General Practice, Universidad Estatal de Guayaquil, Machala, ECU.
Cureus. 2024 Aug 1;16(8):e65919. doi: 10.7759/cureus.65919. eCollection 2024 Aug.
Genetics can influence obesity, and when it affects both parents and children, there is a high risk of developing cardiometabolic diseases. Studies have indicated that family-based treatment (FBT) is a cost-effective and successful option for achieving significant weight changes in both children and parents. While specialized clinics offer FBT, primary care settings, where most pediatric care takes place, may not have the necessary resources or expertise to provide intensive behavioral interventions for childhood obesity. Based on early findings, FBT could potentially have a positive impact on siblings as well, as when treated children and parents experience behavioral changes, it can also have a beneficial effect on their untreated siblings. Parents play a crucial role in shaping their children's behavior, and siblings often have a stronger influence on them than their parents or friends. For our meta-analysis, we utilized three graphical models created using RevMan 5.4, based on the selected articles. To develop our systematic review, we thoroughly analyzed a total of 10 articles. The subgroup analysis within these studies assessed the effectiveness of FBT for overweight children, revealing no significant differences between groups (p=0.77). This suggests that based on their BMI, FBT may not have a statistically significant impact on weight loss in overweight children. However, each study reviewed showed statistical significance (p<0.05). The findings of our meta-analysis underscore the need for more robust evidence and larger randomized controlled trials (RCTs) to enhance our understanding of FBT's benefits in pediatric obesity. This will be crucial for reducing the rising prevalence of obesity and maintaining lower incidence rates.
遗传学可影响肥胖，当它同时影响父母和子女时，患心脏代谢疾病的风险很高。研究表明，基于家庭的治疗（FBT）是一种具有成本效益且成功的方法，可使儿童和父母都实现显著的体重变化。虽然专业诊所提供FBT，但大多数儿科护理发生的初级保健机构可能没有必要的资源或专业知识来为儿童肥胖提供强化行为干预。根据早期研究结果，FBT可能对兄弟姐妹也有积极影响，因为接受治疗的儿童和父母出现行为改变时，也会对未接受治疗的兄弟姐妹产生有益影响。父母在塑造孩子行为方面起着至关重要的作用，而且兄弟姐妹对他们的影响往往比父母或朋友更大。在我们的荟萃分析中，我们基于所选文章，利用RevMan 5.4创建了三个图形模型。为了开展我们的系统评价，我们对总共10篇文章进行了全面分析。这些研究中的亚组分析评估了FBT对超重儿童的有效性，结果显示组间无显著差异（p = 0.77）。这表明，基于体重指数，FBT可能对超重儿童的体重减轻没有统计学上的显著影响。然而，每篇纳入综述的研究均显示具有统计学显著性（p<0.05）。我们荟萃分析的结果强调，需要更有力的证据和更大规模的随机对照试验（RCT）来加深我们对FBT在儿童肥胖症中益处的理解。这对于降低肥胖症患病率的上升和维持较低的发病率至关重要。
