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Unna 靴对静脉性溃疡愈合的影响:系统评价和荟萃分析。

Effect of Unna's boot on venous ulcer healing: a systematic review and meta-analysis.

机构信息

Universidade Federal do Rio Grande do Sul, Escola de Enfermagem, Porto Alegre, RS, Brazil.

Universidade Federal de São Paulo, Biblioteca, São Paulo, SP, Brazil.

出版信息

Rev Esc Enferm USP. 2024 Sep 2;58:e20230397. doi: 10.1590/1980-220X-REEUSP-2023-0397en. eCollection 2024.

Abstract

OBJECTIVE

To analyze the effect of Unna's Boot on the healing of venous ulcers compared to other therapies.

METHODS

Systematic Review carried out in the databases Scopus, Embase, Cochrane Library, Web of Science, PubMed, Cumulative Index of Nursing and Allied Health Literature, Latin American and Caribbean Literature in Health Sciences, and grey literature. Population - adult patients with venous ulcers; Intervention- Unna's Boot (UB); Control - other compression therapies (CT); Outcome- healing; Designs- randomized clinical trial, cohort study, and case control, published from 2001 to 2024. The effect of the intervention, risk of bias, and quality of evidence were evaluated. Registered with PROSPERO (CRD42021290077).

RESULTS

A total of 39 studies were included, with 5.151 patients. The majority (71.8%) were randomized controlled trials (RCT). UB was used as intervention/control in eight studies. When comparing CTs, only 1 study with UB showed a superior effect (p < .001) in healing, compared with high compression elastic bandage. In the quality of evidence analysis, 27 studies were assessed as having a high risk of bias.

CONCLUSION

No superiority of UB was found in the healing of venous ulcers when compared to other CTs.

摘要

目的

分析与其他疗法相比,尤娜氏靴(Unna's Boot)对静脉溃疡愈合的影响。

方法

在 Scopus、Embase、Cochrane 图书馆、Web of Science、PubMed、护理和联合健康文献累积索引、拉丁美洲和加勒比健康科学文献以及灰色文献数据库中进行系统评价。人群-患有静脉溃疡的成年患者;干预措施-尤娜氏靴(UB);对照组-其他压缩疗法(CT);结局-愈合;设计-随机临床试验、队列研究和病例对照研究,发表时间为 2001 年至 2024 年。评估干预效果、偏倚风险和证据质量。在 PROSPERO(CRD42021290077)中进行了注册。

结果

共纳入 39 项研究,共计 5151 例患者。其中大多数(71.8%)为随机对照试验(RCT)。有 8 项研究将 UB 用作干预/对照。在比较 CT 时,只有 1 项使用 UB 的研究在愈合方面显示出优于高压缩弹性绷带的效果(p<0.001)。在证据质量分析中,有 27 项研究被评估为存在高偏倚风险。

结论

与其他 CT 相比,UB 在静脉溃疡愈合方面没有优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0104/11368076/9eb41801a880/1980-220X-reeusp-58-e20230397-gf01.jpg

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