Department of Bioethics & Health Humanities, Julius Center for Health Sciences & Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Department of Orthopedic Surgery, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Regen Med. 2024;19(7-8):393-406. doi: 10.1080/17460751.2024.2386214. Epub 2024 Sep 2.
Perspectives of patients, parents and professional experts on personalized regenerative implants for regenerative medicine purposes are largely unknown. To better understand these perspectives, we conducted four focus groups with professional experts of mixed European nationality (n = 8), Dutch patients with regular implants (n = 8), Dutch and Belgian (n = 5) and Spanish (n = 8) parents of children with cleft palate. Two overarching themes were identified: 'patient-centered research and care' and 'ambivalent attitudes toward personalized regenerative implants'. The results reveal that stakeholders should adopt a participatory rather than an impairment discourse and address the ambivalence among professional experts, patients and parents. Considering stakeholder perspectives facilitates ethical and responsible development and use of personalized regenerative implants.
患者、家长和专业专家对再生医学目的的个性化再生植入物的看法在很大程度上是未知的。为了更好地理解这些观点，我们进行了四项焦点小组的研究，参与者包括具有混合国籍的专业专家（n=8）、荷兰有常规植入物的患者（n=8）、荷兰和比利时（n=5）以及西班牙（n=8）腭裂患儿的家长。确定了两个总体主题：“以患者为中心的研究和护理”和“对个性化再生植入物的矛盾态度”。研究结果表明，利益相关者应该采取参与式而不是损伤性的话语，并解决专业专家、患者和家长之间的矛盾。考虑到利益相关者的观点，可以促进个性化再生植入物的伦理和负责任的开发和使用。
