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心脏外科手术出血、输血与质量指标:术后加速康复心脏协会和患者血液管理促进协会联合共识声明

Cardiac Surgical Bleeding, Transfusion, and Quality Metrics: Joint Consensus Statement by the Enhanced Recovery After Surgery Cardiac Society and Society for the Advancement of Patient Blood Management.

作者信息

Salenger Rawn, Arora Rakesh C, Bracey Arthur, D'Oria Mario, Engelman Daniel T, Evans Caroline, Grant Michael C, Gunaydin Serdar, Morton Vicki, Ozawa Sherri, Patel Prakash A, Raphael Jacob, Rosengart Todd K, Shore-Lesserson Linda, Tibi Pierre, Shander Aryeh

机构信息

Division of Cardiac Surgery, University of Maryland Saint Joseph Medical Center, Towson, Maryland.

Division of Cardiac Surgery, Harrington Heart and Vascular Institute, University Hospitals, Cleveland, Ohio.

出版信息

Ann Thorac Surg. 2025 Feb;119(2):280-295. doi: 10.1016/j.athoracsur.2024.06.039. Epub 2024 Aug 31.

DOI:
10.1016/j.athoracsur.2024.06.039
PMID:39222899
Abstract

BACKGROUND

Excessive perioperative bleeding is associated with major complications in cardiac surgery, resulting in increased morbidity, mortality, and cost.

METHODS

An international expert panel was convened to develop consensus statements on the control of bleeding and management of transfusion and to suggest key quality metrics for cardiac surgical bleeding. The panel reviewed relevant literature from the previous 10 years and used a modified RAND Delphi methodology to achieve consensus.

RESULTS

The panel developed 30 consensus statements in 8 categories, including prioritizing control of bleeding, prechest closure checklists, and the need for additional quality indicators beyond reexploration rate, such as time to reexploration. Consensus was also reached on the need for a universal definition of excessive bleeding, the use of antifibrinolytics, optimal cessation of antithrombotic agents, and preoperative risk scoring based on patient and procedural factors to identify those at greatest risk of excessive bleeding. Furthermore, an objective bleeding scale is needed based on the volume and rapidity of blood loss accompanied by viscoelastic management algorithms and standardized, patient-centered blood management strategies reflecting an interdisciplinary approach to quality improvement.

CONCLUSIONS

Prioritizing the timely control and management of bleeding is essential to improving patient outcomes in cardiac surgery. To this end, a cardiac surgical bleeding quality metric that is more comprehensive than reexploration rate alone is needed. Similarly, interdisciplinary quality initiatives that seek to implement enhanced quality indicators will likely lead to improved patient care and outcomes.

摘要

背景

围手术期出血过多与心脏手术的主要并发症相关,会导致发病率、死亡率上升及成本增加。

方法

召集了一个国际专家小组,以制定关于出血控制和输血管理的共识声明,并提出心脏手术出血的关键质量指标。该小组回顾了过去10年的相关文献,并采用改良的兰德德尔菲方法达成共识。

结果

该小组在8个类别中制定了30条共识声明,包括优先控制出血、胸部闭合前检查清单,以及除再次手术率之外还需要其他质量指标,如再次手术时间。对于出血过多的通用定义、抗纤溶药物的使用、抗血栓药物的最佳停用,以及基于患者和手术因素的术前风险评分以识别出血过多风险最高的患者,也达成了共识。此外,需要基于失血量和失血速度的客观出血量表,以及反映跨学科质量改进方法的粘弹性管理算法和标准化、以患者为中心的血液管理策略。

结论

优先及时控制和管理出血对于改善心脏手术患者的预后至关重要。为此,需要一个比单纯的再次手术率更全面的心脏手术出血质量指标。同样,寻求实施强化质量指标的跨学科质量倡议可能会改善患者护理和预后。

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